Studying the Sensitivity of Graphene for Biosensor Applications

被引：0
|
作者：
Usikov, A. S. [1 ,2 ]
Lebedev, S. P. [3 ]
Roenkov, A. D. [4 ]
Barash, I. S. [3 ,4 ]
Novikov, S., V [5 ]
Puzyk, M., V [6 ]
Zubov, A., V [2 ]
Makarov, Yu N. [1 ]
Lebedev, A. A. [3 ]
机构：
[1] Nitride Crystals Inc, Richmond, VA 23238 USA
[2] St Petersburg Natl Res Univ Informat Technol Mech, St Petersburg 197101, Russia
[3] Russian Acad Sci, Ioffe Phys Tech Inst, St Petersburg 194021, Russia
[4] Nitride Crystals Grp, St Petersburg 194156, Russia
[5] Aalto Univ, Espoo, Finland
[6] Herzen State Pedag Univ, St Petersburg 191186, Russia
来源：
TECHNICAL PHYSICS LETTERS | 2020年 / 46卷 / 05期
关键词：
graphene; silicon carbide; biosensor; fluorescein;
D O I：
10.1134/S1063785020050296
中图分类号：
O59 [应用物理学];
学科分类号：
摘要：
We have studied the response of graphene-film-based chips on SiC substrates (the relative change in the chip resistance) to coming into contact with fluorescein (C20H12O5) in a wide range of its concentrations in a phosphate-buffered saline solution: from 1 x 10(-3)to 1 x 10(4)ng/mL (seven orders of magnitude). Fluorescein detection seems to be a simple and cheap model experiment to study the sensory ability of graphene in the way of biochips manufacturing. It has been shown that chips with wide terraces on a surface with a step width of about 1000 nm and heights of up to 5 nm made it possible to construct the calibration dependences of chip response on fluorescein concentration.
引用
收藏
页码：462 / 465
页数：4
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