Gut microbiota influence in type 2 diabetes mellitus (T2DM)

被引：116
|
作者：
Cunningham, A. L. [1 ,2 ]
Stephens, J. W. [1 ,2 ]
Harris, D. A. [1 ,2 ]
机构：
[1] Swansea Bay Univ, Hlth Board, Dept Surg, Singleton Hosp, Swansea SA2 8QA, W Glam, Wales
[2] Swansea Univ, Sch Med, Inst Life Sci 2, Med Sch, Swansea SA2 8QA, W Glam, Wales
来源：
GUT PATHOGENS | 2021年 / 13卷 / 01期
关键词：
Gut microbiota; Type two diabetes mellitus; CHAIN FATTY-ACIDS; GLUCAGON-LIKE PEPTIDE-1; DIET-INDUCED OBESITY; GROWTH-FACTORS; 15/19; INTESTINAL MICROBIOTA; INSULIN SENSITIVITY; BODY-WEIGHT; HUMAN COLON; EARLY-ONSET; BILE-ACIDS;
D O I：
10.1186/s13099-021-00446-0
中图分类号：
R57 [消化系及腹部疾病];
学科分类号：
摘要：
A strong and expanding evidence base supports the influence of gut microbiota in human metabolism. Altered glucose homeostasis is associated with altered gut microbiota, and is clearly associated with the development of type 2 diabetes mellitus (T2DM) and associated complications. Understanding the causal association between gut microbiota and metabolic risk has the potential role of identifying susceptible individuals to allow early targeted intervention.
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页数：13
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