A facile solid phase synthesis of tetramic acid

被引：20

作者：

Liu, ZX ^{[1
]}

Ruan, XX ^{[1
]}

Huang, X ^{[1
]}

机构：

[1] Zhejiang Univ, Dept Chem, Hangzhou 310028, Peoples R China

来源：

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS | 2003年 / 13卷 / 15期

关键词：

D O I：

10.1016/S0960-894X(03)00502-X

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

The condensation of N-acylated amino acids with polymer-supported cyclic malonic acid ester was carried out in the presence of DCC/DMAP. The cyclisation of the intermediate resin, by heating in an organic solvent, gave the N-protected tetramic acid derivatives in good yields and high purity. (C) 2003 Elsevier Ltd. All rights reserved.

引用

下载

页码：2505 / 2507

页数：3

共 50 条

[1] Solid-phase synthesis of tetramic acids
Kulkarni, BA
Ganesan, A
TETRAHEDRON LETTERS, 1998, 39 (24) : 4369 - 4372
[2] Solid-phase synthesis of substituted tetramic acids
Matthews, J
Rivero, RA
JOURNAL OF ORGANIC CHEMISTRY, 1998, 63 (14): : 4808 - 4810
[3] Toward the synthesis of magnesidin, a tetramic acid
Pingali, Subramanya Ravi Kiran
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2010, 240
[4] Solid-Phase Synthesis of Tetramic Acid via Resin-Bound Enol Ethers as a Privileged Scaffold in Drug Discovery
Schutznerova, Eva
Oliver, Allen G.
Pribylka, Adam
Krchnak, Viktor
ADVANCED SYNTHESIS & CATALYSIS, 2018, 360 (19) : 3693 - 3699
[5] Novel chiral tetramic acid-derived diols: organocatalytic facile synthesis and unique structural properties
Sengoku, Tetsuya
Suzuki, Kosuke
Nakayama, Ken
Yagishita, Fumitoshi
Sakamoto, Masami
Takahashi, Masaki
Yoda, Hidemi
RSC ADVANCES, 2014, 4 (58): : 30775 - 30779
[6] A concise, asymmetric synthesis of tetramic acid derivatives
Fustero, S
de la Torre, MG
Sanz-Cervera, JF
de Arellano, CR
Piera, J
Simón, A
ORGANIC LETTERS, 2002, 4 (21) : 3651 - 3654
[7] SYNTHESIS AND REACTIVITY OF TETRAMIC ACID-DERIVATIVES
HENTSCHEL, C
BUCHHOLZ, H
GELBIN, A
KOPPE, A
HENNING, HG
ZEITSCHRIFT FUR CHEMIE, 1988, 28 (07): : 260 - 260
[8] Total Synthesis of the Diglycosidic Tetramic Acid Ancorinoside A
Petermichl, Markus
Schobert, Rainer
CHEMISTRY-A EUROPEAN JOURNAL, 2017, 23 (59) : 14743 - 14746
[9] Solid phase synthesis of substituted tetramic acids using heterocyclic N-oxide chemistry
Nie, X
Gao, Y
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 1999, 217 : U132 - U132
[10] Facile solid-phase synthesis of an antifreeze glycoprotein
Tseng, PH
Jiaang, WT
Chang, MY
Chen, ST
CHEMISTRY-A EUROPEAN JOURNAL, 2001, 7 (03) : 585 - 590

← 1 2 3 4 5 →