High resolution 3D dosimetry for microbeam radiation therapy using optical CT

被引:1
|
作者
McErlean, C. [1 ]
Braeuer-Krisch, E. [2 ]
Adamovics, J. [3 ,6 ]
Leach, M. O. [1 ,4 ]
Doran, S. J. [1 ,5 ]
机构
[1] Inst Canc Res, CRUK Canc Imaging Ctr, London SW3 6JB, England
[2] European Synchrotron Radiat Facil, F-38043 Grenoble, France
[3] Rider Univ, Dept Chem & Biol, Lawrenceville, NJ 08648 USA
[4] Royal Marsden NHS Trust, Clin Magnet Resonance Res Grp, London, England
[5] Univ Surrey, Dept Phys, Guildford GU2 5XH, Surrey, England
[6] Heuris Pharma LLC, Skillman, NJ 08558 USA
关键词
TOMOGRAPHY;
D O I
10.1088/1742-6596/573/1/012032
中图分类号
R318 [生物医学工程];
学科分类号
0831 ;
摘要
Optical Computed Tomography (CT) is a promising technique for dosimetry of Microbeam Radiation Therapy (MRT), providing high resolution 3D dose maps. Here different MRT irradiation geometries are visualised showing the potential of Optical CT as a tool for future MRT trials. The Peak-to-Valley dose ratio (PVDR) is calculated to be 7 at a depth of 3mm in the radiochromic dosimeter PRESAGE (R). This is significantly lower than predicted values and possible reasons for this are discussed.
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页数:4
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