Performance of a rapid antigen test for the diagnosis of congenital malaria

被引：8

作者：

Sotimehin, Sikirat A.

Runsewe-Abiodun, Tamrat I.

Oladapo, Olufemi T.

Njokanma, Olisamedua F.

Olanrewaju, Duro M.

机构：

[1] Obafemi Awolowo Univ, Coll Hlth Sci, Dept Pediat, Olabisi Onabanjo Univ Teaching Hosp, Shagamu, Nigeria

[2] Obafemi Awolowo Univ, Coll Hlth Sci, Dept Obstet & Gynecol, Olabisi Onabanjo Univ Teaching Hosp, Shagamu, Nigeria

[3] Lagos State Univ Teaching Hosp, Ikeja, Nigeria

来源：

ANNALS OF TROPICAL PAEDIATRICS | 2007年 / 27卷 / 04期

关键词：

D O I：

10.1179/146532807X245698

中图分类号：

R72 [儿科学];

学科分类号：

100202 ;

摘要：

Objective: To assess the performance of OptiMAL (R), a rapid malaria antigen capture dipstick, in diagnosing congenital malaria. Methods: Live newborns aged 0-3 days, delivered at Olabisi Onabanjo University Teaching Hospital, Sagamu, Nigeria between August 2004 and January 2005, were screened for malaria parasitaemia with an immuno-chromatographic test (OptiMAL (R)) and blood film microscopy. OptiMAL (R) detects plasmodium lactate dehydrogenase (pLDH). Results: Twenty-one of 192 newborns (10.9%) were diagnosed with congenital malaria by blood film microscopy. The OptiMAL (R) test was negative in all infants. Conclusion: OptiMAL (R) rapid malaria antigen capture dipstick might not be useful for diagnosing malaria parasitaemia in newborns. Blood film microscopy remains the gold standard for the diagnosis of congenital malaria.

引用

页码：297 / 301

页数：5

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