An efficient one-pot synthesis of tetra-substituted pyrroles

被引：62

作者：

Ghabraie, Elmira ^{[1
]}

Balalaie, Saeed ^{[1
]}

Bararjanian, Morteza ^{[1
]}

Bijanzadeh, Hamid Reza ^{[2
]}

Rominger, Frank ^{[3
]}

机构：

[1] KN Toosi Univ Technol, Peptide Chem Res Ctr, Tehran, Iran

[2] Tarbiat Modares Univ, Dept Chem, Tehran, Iran

[3] Univ Heidelberg, Inst Organ Chem, D-69120 Heidelberg, Germany

来源：

TETRAHEDRON | 2011年 / 67卷 / 30期

关键词：

Tetra-substituted pyrrole; Iron(III) chloride; beta-Nitrostyrene; One-pot three-component reaction; Enaminone; POLYSUBSTITUTED PYRROLES; AQUEOUS-MEDIA; DERIVATIVES;

D O I：

10.1016/j.tet.2011.05.076

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The three-component reaction of primary amines, dialkyl acetylenedicarboxylates and beta-nitrostyrene derivatives in the presence of Iron(III) chloride afforded 1,2,3,4-tetra-substituted pyrroles in high yields. These reactions could precede via domino Michael addition/cyclization process. (C) 2011 Elsevier Ltd. All rights reserved.

引用

页码：5415 / 5420

页数：6

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