Selection of the R263K mutation to dolutegravir in cerebrospinal fluid HIV-1 virus in one patient with HIV-associated neurocognitive disorders

被引:2
|
作者
Vassallo, Matteo [1 ]
De Monte, Anne [2 ]
Durant, Jacques [3 ]
Dunais, Brigitte [4 ]
Cottalorda, Jacqueline [2 ]
机构
[1] Cannes Gen Hosp, Dept Internal Med Infect Dis, Cannes, France
[2] Nice Univ Hosp, Virol Unit, Nice, France
[3] Nice Univ Hosp, Dept Infect Dis, Nice, France
[4] Nice Univ Hosp, Dept Publ Hlth, Nice, France
关键词
RESISTANCE SUBSTITUTIONS; VIRAL REPLICATION; CAPACITY;
D O I
10.1097/QAD.0000000000001194
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
引用
收藏
页码:2257 / 2258
页数:2
相关论文
共 50 条
  • [11] The cross-talk of HIV-1 Tat and methamphetamine in HIV-associated neurocognitive disorders
    Mediouni, Sonia
    Marcondes, Maria Cecilia Garibaldi
    Miller, Courtney
    McLaughlin, Jay P.
    Valente, Susana T.
    FRONTIERS IN MICROBIOLOGY, 2015, 6
  • [12] An initial screening for HIV-associated neurocognitive disorders of HIV-1 infected patients in China
    Zhang, Yulin
    Qiao, Luxin
    Ding, Wei
    Wei, Feili
    Zhao, Qingxia
    Wang, Xicheng
    Shi, Ying
    Li, Ning
    Smith, Davey
    Chen, Dexi
    JOURNAL OF NEUROVIROLOGY, 2012, 18 (02) : 120 - 126
  • [13] The R263K Dolutegravir Resistance-Associated Substitution Progressively Decreases HIV-1 Integration (vol 8, e00157-17, 2017)
    Mesplede, Thibault
    Leng, Jing
    Hanh Thi Pham
    Liang, Jiaming
    Quan, Yudong
    Han, Yingshan
    Wainberg, Mark A.
    MBIO, 2018, 9 (05):
  • [14] Characterization of the R263K Mutation in HIV-1 Integrase That Confers Low-Level Resistance to the Second-Generation Integrase Strand Transfer Inhibitor Dolutegravir
    Quashie, Peter K.
    Mesplede, Thibault
    Han, Ying-Shan
    Oliveira, Maureen
    Singhroy, Diane N.
    Fujiwara, Tamio
    Underwood, Mark R.
    Wainberg, Mark A.
    JOURNAL OF VIROLOGY, 2012, 86 (05) : 2696 - 2705
  • [15] HIV-1 infection alters energy metabolism in the brain: Contributions to HIV-associated neurocognitive disorders
    Cotto, Bianca
    Natarajanseenivasan, Kalimuthusamy
    Langford, Dianne
    PROGRESS IN NEUROBIOLOGY, 2019, 181
  • [16] The G118R plus R263K Combination of Integrase Mutations Associated with Dolutegravir-Based Treatment Failure Reduces HIV-1 Replicative Capacity and Integration
    Xiao, Meng A.
    Cleyle, Jenna
    Yoo, Sunbin
    Forrest, Mekayla
    Krullaars, Zoe
    Pham, Hanh Thi
    Mesplede, Thibault
    ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 2023, 67 (05)
  • [17] Modulation of HIV-1 Replication, Inflammation, and Neurotoxicity by a Tobacco Cembranoid 4R: Therapeutic Implications for HIV-Associated Neurocognitive Disorders
    Rodriguez, Myosotys
    Eterovic, Vesna A.
    Ferchmin, Pedro A.
    Rios-Olivares, Eddy
    Wang, David
    Nath, Avindra
    Rodriguez, Jose W.
    JOURNAL OF NEUROVIROLOGY, 2010, 16 : 73 - 73
  • [18] Primary mutations in HIV integrase that confer resistance to raltegravir (RAL) and elvitegravir (EVG) are incompatible with the R263K mutation that is associated with low-level resistance to dolutegravir
    Anstett, K.
    Mesplede, T.
    Quashie, P.
    Han, Y.
    Oliveira, M.
    Wainberg, M. A.
    ANTIVIRAL THERAPY, 2014, 19 : A149 - A149
  • [19] Utility of a Short Neuropsychological Protocol for Detecting HIV-Associated Neurocognitive Disorders in Patients with Asymptomatic HIV-1 Infection
    Martinez-Banfi, Martha
    Velez, Jorge, I
    Mebarak Chams, Moises R.
    Arcos-Holzinger, Mauricio
    Acosta-Lopez, Johan E.
    Garcia, Ricardo
    Victoria Perea, Maria
    Arcos-Burgos, Mauricio
    Ladera, Valentina
    BRAIN SCIENCES, 2021, 11 (08)
  • [20] Selection in culture of HIV resistance to dolutegravir by mutations at integrase positions R263K and H51Y that diminish viral replication fitness
    Mesplede, T.
    Quashie, P.
    Oliveira, M.
    Underwood, M.
    Wang, R.
    Fujiwara, T.
    Seki, T.
    Wainberg, M.
    JOURNAL OF THE INTERNATIONAL AIDS SOCIETY, 2012, 15 : 8 - 9