Recent Advances in the Chemistry of Pyrazoles. Properties, Biological Activities, and Syntheses

被引:285
|
作者
Schmidt, Andreas [1 ]
Dreger, Andrij [1 ]
机构
[1] Tech Univ Clausthal, Inst Organ Chem, D-38678 Clausthal Zellerfeld, Germany
关键词
Condensation; Diazo Compounds; 1,3-Dipolar Cycloaddition; Hydrazines; N-Heterocyclic Carbene; Natural Products; Rearrangement; Regiochemistry; ONE-POT SYNTHESIS; MICROWAVE-ASSISTED SYNTHESIS; ELECTRON-TRANSFER REACTIONS; FLASH VACUUM PYROLYSIS; BASE-MEDIATED REACTION; SOLID-PHASE SYNTHESIS; REGIOSELECTIVE SYNTHESIS; SUBSTITUTED PYRAZOLES; X-RAY; 1,3-DIPOLAR CYCLOADDITION;
D O I
10.2174/138527211795378263
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
Pyrazoles are of considerable interest due to the broad variety of their biological activities. This overview summarizes structures of pharmacologically interesting pyrazoles, natural products, technically applied pyrazoles as well as pyrazole syntheses published during the last decade. In addition, new insights into the properties such as tautomerisms, conformations, pyrolyses and decomposition reactions of pyrazoles are reviewed.
引用
收藏
页码:1423 / 1463
页数:41
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