Ameliorating Effects of a Nopal (Opuntia ficus-indica) Complex on Blood Glucose in db/db Mice

被引：6
|
作者：
Yoon, Jin A. [2 ]
Lee, Sung-Joon [3 ]
Kim, Han-Kyeom [4 ]
Son, Yong-Suk [1 ]
机构：
[1] Korea Univ, Div Biotechnol, Coll Life Sci & Biotechnol, Seoul 136713, South Korea
[2] Baewha Womens Univ, Dept Food & Nutr, Seoul 110735, South Korea
[3] Korea Univ, Coll Life Sci & Biotechnol, Div Food Biosci & Technol, Seoul 136713, South Korea
[4] Korea Univ, Guro Hosp, Dept Pathol, Korea Lung Tissue Bank, Seoul 152703, South Korea
来源：
FOOD SCIENCE AND BIOTECHNOLOGY | 2011年 / 20卷 / 01期
关键词：
Opuntia ficus-indica; hypoglycemic; insulin; pancreatic islet; db/db mice; BIOLOGICAL PARAMETERS; SUPPLEMENTED DIET; LIPID PROFILE; DIABETIC-RATS; INSULIN;
D O I：
10.1007/s10068-011-0035-4
中图分类号：
TS2 [食品工业];
学科分类号：
0832 ;
摘要：
This study investigated the effects of a nopal (Opuntia ficus-indica) complex (OF) on blood glucose metabolism in db/db mice for 4 weeks. Food and water intake significantly decreased in OF-treated mice compared to controls (p < 0.05). In addition, blood glucose and plasma insulin levels were significantly reduced in the OF-treated group compared to the controls (p < 0.05). Histopathological analysis showed that the morphology of pancreatic islets was improved in the OF-treated db/db mice. Immunohistochemistry of the pancreatic islets showed that insulin production and the number of beta-cells apparently increased.
引用
收藏
页码：255 / 259
页数：5
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