An easy-to-use dry-powder inhaler

被引:11
|
作者
Karpel, JP [1 ]
机构
[1] Montefiore Med Ctr, Albert Einstein Coll Med, Dept Med, Bronx, NY 10467 USA
关键词
asthma; corticosteroid; inhalation therapy; dry-powder inhaler; mometasone furoate; compliance;
D O I
10.1007/BF02850011
中图分类号
R-3 [医学研究方法]; R3 [基础医学];
学科分类号
1001 ;
摘要
The mometasone furoate dry-powder inhaler is a novel device designed to support compliance by delivering a topical corticosteroid in a simple three-step operation. This breath-actuated inhaler uses a stabilized agglomerate formulation to measure and deliver accurate, uniform, and precise doses of drug over a range of inspiratory flow rates. Laboratory and clinical data have shown that the design produced a simple, clinically effective inhaler for the treatment of adults and children 12 years of age and older with mild, moderate, or severe persistent asthma.
引用
收藏
页码:282 / 286
页数:5
相关论文
共 50 条
  • [31] Bronchodilation and bronchoprotection in asthmatic preschool children from formoterol administered by mechanically actuated dry-powder inhaler and spacer
    Nielsen, KG
    Bisgaard, H
    AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 2001, 164 (02) : 256 - 259
  • [32] Suboptimal peak inspiratory flow rate in dry-powder inhaler users for chronic obstructive pulmonary disease in Korea
    Moon, Ji-Yong
    Kim, Sang Hyuk
    Kim, Youlim
    Lee, Hyun
    Rhee, Chin Kook
    Ra, Seung Won
    Lee, Chang Youl
    Park, Joo Hun
    Park, Yong Bum
    Yoo, Kwang Ha
    PULMONARY PHARMACOLOGY & THERAPEUTICS, 2024, 85
  • [33] A NEW DRY POWDER INHALER
    POVER, GM
    BROWNING, AK
    MULLINGER, BM
    BUTLER, AG
    DASH, CH
    PRACTITIONER, 1982, 226 (1365) : 565 - 567
  • [34] Is the correct use of a dry powder inhaler (Turbohaler) age dependent?
    De Boeck, K
    Alifier, M
    Warnier, G
    JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY, 1999, 103 (05) : 763 - 767
  • [35] Clinical effect of Diskus™ dry-powder inhaler at low and high inspiratory flow-rates in asthmatic children
    Nielsen, KG
    Auk, IL
    Bojsen, K
    Ifversen, M
    Klug, B
    Bisgaard, H
    EUROPEAN RESPIRATORY JOURNAL, 1998, 11 (02) : 350 - 354
  • [36] Effect of Human Error, Inhalation Flow, and Inhalation Volume on Dose Delivery from Ellipta® Dry-Powder Inhaler
    Haitham Saeed
    Heba F. Salem
    Hoda Rabea
    Mohamed E. A. Abdelrahim
    Journal of Pharmaceutical Innovation, 2019, 14 : 239 - 244
  • [37] Genuair (R) in chronic obstructive pulmonary disease: a novel, user-friendly, multidose, dry-powder inhaler
    van der Palen, Job
    THERAPEUTIC DELIVERY, 2014, 5 (07) : 795 - 806
  • [38] Comparison of the effect on bronchial hyperresponsiveness of beclomethasone dipropionate administered via a novel multidose dry-powder inhaler or a conventional pressurised metered dose inhaler
    Morice, AH
    Andrews, B
    Taylor, M
    RESPIRATION, 2000, 67 (03) : 298 - 305
  • [39] REDUCTION OF COSTS ASOCIATED WITH A NEW DRY-POWDER INHALER FORMULATION WITH BECLOMETHASONE DIPROPIONATE AND FORMOTEROL COMBINATION FOR THE TREATMENT OF ASTHMA
    Sanz-Granda, A.
    Hidalgo, A.
    VALUE IN HEALTH, 2013, 16 (07) : A368 - A368
  • [40] Development of a Rational Design Space for Optimizing Mixing Conditions for Formation of Adhesive Mixtures for Dry-Powder Inhaler Formulations
    Sarkar, Saurabh
    Minatovicz, Bruna
    Thalberg, Kyrre
    Chaudhuri, Bodhisattwa
    JOURNAL OF PHARMACEUTICAL SCIENCES, 2017, 106 (01) : 129 - 139