Hereditary endometrial cancer: a case report

Introduction: Endometrial cancer (EC) is one of the commonest malignancies of the female reproductive tract. In recent years, the heredity and familial clustering of EC has been described by researchers, but few cases are reported from China. Cases Report: A 50-years-old Chinese women presented with irregular vagina bleeding for more than 20 days. The clinical impression was EC and she was treated by surgery and chemotherapy. Four years later, her mother and two sisters were also diagnosed with EC in the same hospital. The authors therefore summarized the case profiles of this family to learn more about familial hereditary EC. Conclusion: The authors present four cases of hereditary EC from one family pedigree. For individuals who have a family history of EC, it is necessary to promote molecular genetic test and gynecological screening for early detection and prevention.