Fabrication of nanofiber mats with microstructure gradient by cone electrospinning

被引:9
|
作者
Zhou, Yingge [1 ]
Tan, George Z. [1 ]
机构
[1] Texas Tech Univ, Dept Ind Mfg & Syst Engn, Lubbock, TX 79409 USA
来源
NANOMATERIALS AND NANOTECHNOLOGY | 2017年 / 7卷
关键词
Electrospinning; nanomanufacturing; nanofibers; microstructure gradient; bioscaffold; FIBER DIAMETER; PORE-SIZE; SCAFFOLDS; TISSUE; BONE; MEMBRANES; MESHES;
D O I
10.1177/1847980417748478
中图分类号
TB3 [工程材料学];
学科分类号
0805 ; 080502 ;
摘要
As a versatile nanofiber manufacturing technique, electrospinning has been widely used for tissue engineering scaffold fabrication. However, it remains challenging to create scaffolds with anisotropic microstructure close to native tissues. This article presented a novel electrospinning configuration to generate fibrous mat with microstructure gradient. A series of proof-of-concept tests were performed to investigate the effects of process parameters on the gradient of nanofiber morphology and mat attributes. The technique developed in this study showed great potentials as a fabrication platform for heterogenous nanofiber products.
引用
收藏
页数:8
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