Time to eat reveals the hierarchy of peripheral clocks

被引：19

作者：

Zhang, Zhihui ^{[1
,2
]}

Shui, Guanghou ^{[3
]}

Li, Min-Dian ^{[1
,2
,4
,5
]}

机构：

[1] Army Med Univ, Dept Cardiol, Southwest Hosp, Third Mil Med Univ, Chongqing 400038, Peoples R China

[2] Army Med Univ, Ctr Circadian Metab & Cardiovasc Dis, Southwest Hosp, Third Mil Med Univ, Chongqing 400038, Peoples R China

[3] Chinese Acad Sci, Inst Genet & Dev Biol, State Key Lab Mol Dev Biol, Beijing 100101, Peoples R China

[4] Army Med Univ, Inst Pathol, Third Mil Med Univ, Southwest Hosp, Chongqing 400038, Peoples R China

[5] Army Med Univ, Southwest Canc Ctr, Third Mil Med Univ, Southwest Hosp, Chongqing 400038, Peoples R China

来源：

TRENDS IN CELL BIOLOGY | 2021年 / 31卷 / 11期

基金：

中国国家自然科学基金;

关键词：

HEPATIC CIRCADIAN CLOCK;

D O I：

10.1016/j.tcb.2021.08.003

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

Meal timing resets trillions of cellular circadian clocks in the body. Recent advances in multiomics demonstrate that clocks in peripheral tissues are differentially reset by feeding rhythm, and modulated by the central clock and the liver clock. This highlights the essential roles of tissue-specific regulation and intercellular signaling in clock synchronization.

引用

页码：869 / 872

页数：4

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