Angioedema associated with nonsteroidal anti-inflammatory drugs

被引：13
|
作者：
Giavina-Bianchi, Pedro [1 ,2 ]
Aun, Marcelo Vivolo [1 ,2 ]
Jose Jares, Edgardo [3 ]
Kalil, Jorge [1 ,2 ]
机构：
[1] Clin Immunol & Allergy Div, Sao Paulo, Brazil
[2] Univ Sao Paulo, Sao Paulo, Brazil
[3] CMP SA, Libra Fdn, Allergy Unit, Buenos Aires, DF, Argentina
来源：
CURRENT OPINION IN ALLERGY AND CLINICAL IMMUNOLOGY | 2016年 / 16卷 / 04期
关键词：
Anaphylaxis; angioedema; hypersensitivity reactions; NSAIDs; urticaria; URTICARIA AND/OR ANGIOEDEMA; ASPIRIN-INDUCED URTICARIA; HYPERSENSITIVITY REACTIONS; NONIMMEDIATE REACTIONS; INDUCED ANAPHYLAXIS; GENETIC-VARIANTS; CLASSIFICATION; NSAIDS; DIAGNOSIS; IMMEDIATE;
D O I：
10.1097/ACI.0000000000000292
中图分类号：
R392 [医学免疫学];
学科分类号：
100102 ;
摘要：
Purpose of review The review critically assesses the different phenotypes of angioedemas associated with NSAIDs. Angioedemas exacerbated or induced by NSAIDs have high morbidity and, when they affect the larynx, can lead to death by asphyxiation. Recent findings Angioedema can present as a manifestation of a syndrome such as anaphylaxis or it can be a separate entity, which comprises different forms that can be diagnosed based on specific criteria. NSAIDs are the drugs most used worldwide and they are also one of the leading causes of angioedema. Summary The manuscript addresses the pathophysiology and pharmacogenetics of angioedema, reviews its classification and assesses the diagnosis and management of angioedemas exacerbated and induced by NSAIDs.
引用
收藏
页码：323 / 332
页数：10
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