GATA Switches as Developmental Drivers

被引：221

作者：

Bresnick, Emery H. ^{[1
,2
]}

Lee, Hsiang-Ying ^{[1
,2
]}

Fujiwara, Tohru ^{[1
,2
]}

Johnson, Kirby D. ^{[1
,2
]}

Keles, Sunduz ^{[3
]}

机构：

[1] Univ Wisconsin, Sch Med & Publ Hlth, Paul Carbone Comprehens Canc Ctr, Div Hematol Oncol,Dept Pharmacol, Madison, WI 53705 USA

[2] Univ Wisconsin, Sch Med & Publ Hlth, Paul Carbone Comprehens Canc Ctr, Dept Med, Madison, WI 53705 USA

[3] Univ Wisconsin, Sch Med & Publ Hlth, Dept Biostat & Med Informat, Madison, WI 53706 USA

来源：

JOURNAL OF BIOLOGICAL CHEMISTRY | 2010年 / 285卷 / 41期

基金：

美国国家卫生研究院;

关键词：

TRANSCRIPTION FACTOR GATA-1; CHROMATIN DOMAIN ACTIVATION; ZINC-FINGER PROTEIN; DNA-BINDING; GENE-EXPRESSION; ERYTHROID DEVELOPMENT; DEPENDENT REGULATION; HEMATOPOIETIC-CELLS; FACTOR INTERPLAY; GLOBIN LOCUS;

D O I：

10.1074/jbc.R110.159079

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Transcriptional networks orchestrate complex developmental processes. Such networks are commonly instigated by master regulators of development. Considerable progress has been made in elucidating GATA factor-dependent genetic networks that control blood cell development. GATA-2 is required for the genesis and/or function of hematopoietic stem cells, whereas GATA-1 drives the differentiation of hematopoietic progenitors into a subset of the blood cell lineages. GATA-1 directly represses Gata2 transcription, and this involves GATA-1-mediated displacement of GATA-2 from chromatin, a process termed a GATA switch. GATA switches occur at numerous loci with critical functions, indicating that they are widely utilized developmental control tools.

引用

页码：31087 / 31093

页数：7

共 50 条

[31] Developmental differences in megakaryocytopoeisis: The role of GATA-1 short
Poterjoy, Brandon S.
Bailey, Matthew C.
Sola-Visner, Martha C.
BLOOD, 2007, 110 (11) : 86B - 86B
[32] Developmental sources of crash risk in young drivers
Arnett, JJ
INJURY PREVENTION, 2002, 8 : 17 - 21
[33] Fungal oxylipins direct programmed developmental switches in filamentous fungi
Mengyao Niu
Breanne N. Steffan
Gregory J. Fischer
Nandhitha Venkatesh
Nicholas L. Raffa
Molly A. Wettstein
Jin Woo Bok
Claudio Greco
Can Zhao
Erwin Berthier
Ernst Oliw
David Beebe
Michael Bromley
Nancy P. Keller
Nature Communications, 11
[34] Fungal oxylipins direct programmed developmental switches in filamentous fungi
Niu, Mengyao
Steffan, Breanne N.
Fischer, Gregory J.
Venkatesh, Nandhitha
Raffa, Nicholas L.
Wettstein, Molly A.
Bok, Jin Woo
Greco, Claudio
Zhao, Can
Berthier, Erwin
Oliw, Ernst
Beebe, David
Bromley, Michael
Keller, Nancy P.
NATURE COMMUNICATIONS, 2020, 11 (01)
[35] Zebrafish gata2 Orthologs Are Necessary but Not Sufficient for Developmental Hematopoiesis
Pena, Oscar
Rowell, Jasmine
Lemmik, Hanna
Umamahesan, Chianna
Hockings, Catherine
Payne, Elspeth
BLOOD, 2017, 130
[36] The multi-faceted role of Gata3 in developmental haematopoiesis
Zaidan, Nada
Ottersbach, Katrin
OPEN BIOLOGY, 2018, 8 (11):
[37] GATA-dependent regulatory switches establish atrioventricular canal specificity during heart development
Stefanovic, Sonia
Barnett, Phil
van Duijvenboden, Karel
Weber, David
Gessler, Manfred
Christoffels, Vincent M.
NATURE COMMUNICATIONS, 2014, 5
[38] Developmental Systems Drift and the Drivers of Sex Chromosome Evolution
Cauret, Caroline M. S.
Gansauge, Marie-Theres
Tupper, Andrew S.
Furman, Benjamin L. S.
Knytl, Martin
Song, Xue-Ying
Greenbaum, Eli
Meyer, Matthias
Evans, Ben J.
MOLECULAR BIOLOGY AND EVOLUTION, 2020, 37 (03) : 799 - 810
[39] Adolescent drivers - A developmental perspective on risk, proficiency, and safety
Keating, Daniel P.
Halpern-Felsher, Bonnie L.
AMERICAN JOURNAL OF PREVENTIVE MEDICINE, 2008, 35 (03) : S272 - S277
[40] Genetic and developmental drivers of convergent ear loss in toads
Womack, M. C.
Stynoski, J.
Lemmon, A. R.
Lemmon, E. M.
Metz, M.
Hoke, K. L.
INTEGRATIVE AND COMPARATIVE BIOLOGY, 2017, 57 : E448 - E448

← 1 2 3 4 5 →