Rapid detection of vancomycin-resistant enterococci from rectal swabs by the Cepheid Xpert vanA/vanB assay

被引：28
|
作者：
Bourdon, Nancy
Berenger, Raphael
Lepoultier, Romain
Mouet, Audrey
Lesteven, Claire
Borgey, France
Fines-Guyon, Marguerite
Leclercq, Roland
Cattoir, Vincent
机构：
[1] CHU Cote Nacre, Microbiol Serv, Ctr Natl Resistance Antibiot, Lab Associe Enterocoques, F-14033 Caen, France
[2] CHU Cote Nacre, Serv Hyg Hosp, F-14033 Caen, France
[3] CHU Cote Nacre, Reseau Reg Hyg, F-14033 Caen, France
来源：
DIAGNOSTIC MICROBIOLOGY AND INFECTIOUS DISEASE | 2010年 / 67卷 / 03期
关键词：
Real-time PCR; GeneXpertg (R); VRE; vanA; vanB; STAPHYLOCOCCUS-AUREUS; METHICILLIN-RESISTANT; ENTEROVIRUS ASSAY; BLOOD CULTURES; IDENTIFICATION; MRSA; SPECIMENS; VANB;
D O I：
10.1016/j.diagmicrobio.2010.02.009
中图分类号：
R51 [传染病];
学科分类号：
100401 ;
摘要：
The detection of vancomycin-resistant enterococci using a novel commercial multiplex real-time polymerase chain reaction assay (Xpert (TM) vanA/vanB, Cepheid, Sunnyvale, CA) was evaluated on 804 rectal swab specimens. Compared to enriched culture, sensitivity and negative predictive value of this method were 100%. Many false-positive results were recovered (sensitivity, 85.4%; positive predictive value, 8.7%), especially for the vanB gene. (C) 2010 Elsevier Inc. All rights reserved.
引用
收藏
页码：291 / 293
页数：3
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