Intestinal transplant (IT) is one of the least common forms of organ transplant but is increasing both in volume of cases and number of centers performing intestinal transplants, with the busiest centers in North America and Europe. IT can be performed in isolation or as part of a multivisceral transplant (MVT). Intestinal failure either in the form of short gut syndrome or functional bowel problems is the primary indication for IT. The normal post-surgical anatomy can be variable due to both recipient anatomy in regard to amount of residual bowel and status of native vasculature as well as whether the transplant is isolated or part of a multivisceral transplant. Complications of isolated IT and IT as part of an MVT include complications shared with other types of organ transplants such as infection, rejection, post-transplant lymphoproliferative disorder and graft versus host disease. Mechanical bowel complications of the graft include bowel obstruction, stricture, leak, perforation and enterocutaneous fistula. Lastly, vascular complications of both the venous and arterial anastomoses including stricture and pseudoaneurysm occur.
机构:
David Grant USAF, Med Ctr, Travis AFB, CA USADavid Grant USAF, Med Ctr, Travis AFB, CA USA
Walker, D.
Lattin, G.
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Armed Forces Inst Pathol, Washington, DC 20306 USA
Uniformed Serv Univ Hlth Sci, Bethesda, MD 20814 USADavid Grant USAF, Med Ctr, Travis AFB, CA USA
Lattin, G.
Jesinger, R.
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David Grant USAF, Med Ctr, Travis AFB, CA USA
Uniformed Serv Univ Hlth Sci, Bethesda, MD 20814 USADavid Grant USAF, Med Ctr, Travis AFB, CA USA
Jesinger, R.
Tubay, M.
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David Grant USAF, Med Ctr, Travis AFB, CA USA
Univ Utah Hlth Care, Salt Lake City, UT USADavid Grant USAF, Med Ctr, Travis AFB, CA USA
Tubay, M.
Lewis, R.
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Armed Forces Inst Pathol, Washington, DC 20306 USADavid Grant USAF, Med Ctr, Travis AFB, CA USA
Lewis, R.
Dalal, K.
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David Grant USAF, Med Ctr, Travis AFB, CA USADavid Grant USAF, Med Ctr, Travis AFB, CA USA
Dalal, K.
Scherrer, M.
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David Grant USAF, Med Ctr, Travis AFB, CA USADavid Grant USAF, Med Ctr, Travis AFB, CA USA
Scherrer, M.
Grider, D.
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David Grant USAF, Med Ctr, Travis AFB, CA USADavid Grant USAF, Med Ctr, Travis AFB, CA USA