Clozapine in treatment-resistant schizophrenia: a patient's journey

被引:1
|
作者
Korsavva, Sofia [1 ]
Dhadesugur, Seshadri [1 ]
机构
[1] Locked Psychiat Rehabil High Dependency Unit, Cygnet Hlth Care, Wolverhampton, W Midlands, England
关键词
OBSESSIVE-COMPULSIVE SYMPTOMS; QUETIAPINE;
D O I
10.1002/pnp.523
中图分类号
Q189 [神经科学];
学科分类号
071006 ;
摘要
Treatment-resistant schizophrenia can be very difficult to manage and here the authors discuss the treatment challenges in such a patient who has a dual diagnosis of polysubstance abuse. The patient responded to the unusual combination of clozapine, sertraline, quetiapine, valproate semisodium and clonazepam but there were difficulties with the clozapine titration and augmentation. The clinical management lessons are discussed.
引用
收藏
页码:8 / 10
页数:3
相关论文
共 50 条
  • [41] Schizophrenic syndromes and clozapine response in treatment-resistant schizophrenia
    Rodriguez, VM
    Catalina, ML
    García-Noblejas, JA
    Cuesta, P
    [J]. PSYCHIATRY RESEARCH, 1998, 77 (01) : 21 - 28
  • [42] Bromocriptine as adjunctive therapy to clozapine in treatment-resistant schizophrenia
    AlSemaan, Y
    [J]. CANADIAN JOURNAL OF PSYCHIATRY-REVUE CANADIENNE DE PSYCHIATRIE, 1996, 41 (07): : 484 - 485
  • [43] Successful utilization of clozapine for a patient with treatment-resistant schizophrenia after recurrent violent behavior
    Shinohara, Rikuto Christopher
    Oshima, Tomomi
    Otsubo, Takafumi
    Ariga, Keita
    Ono, Tesshu
    Muneoka, Koya
    Umezu, Hiroki
    Mikami, Nobuhiro
    [J]. NEUROPSYCHOPHARMACOLOGY REPORTS, 2024,
  • [44] High doses of aripiprazole therapy for a patient with treatment-resistant schizophrenia responsive to, but intolerant of, clozapine
    Tripathi, Praveen
    Goyal, Priyanka
    Kumar, Deepak
    Prakash, Om
    [J]. AUSTRALIAN AND NEW ZEALAND JOURNAL OF PSYCHIATRY, 2015, 49 (02): : 185 - 185
  • [45] Concurrent administration of clozapine and ECT: A successful therapeutic strategy for a patient with treatment-resistant schizophrenia
    Bhatia, SC
    Bhatia, SK
    Gupta, S
    [J]. JOURNAL OF ECT, 1998, 14 (04) : 280 - 283
  • [46] Clozapine improved the syndrome of inappropriate antidiuretic hormone secretion in a patient with treatment-resistant schizophrenia
    Fujimoto, Michiko
    Hashimoto, Ryota
    Yamamori, Hidenaga
    Yasuda, Yuka
    Ohi, Kazutaka
    Iwatani, Hirotsugu
    Isaka, Yoshitaka
    Takeda, Masatoshi
    [J]. PSYCHIATRY AND CLINICAL NEUROSCIENCES, 2016, 70 (10) : 469 - 469
  • [47] Barriers to using clozapine in treatment-resistant schizophrenia: systematic review
    Farooq, Saeed
    Choudry, Abid
    Cohen, Dan
    Naeem, Farooq
    Ayub, Muhammad
    [J]. BJPSYCH BULLETIN, 2019, 43 (01): : 8 - 16
  • [48] ADJUNCTIVE RISPERIDONE IN CLOZAPINE TREATED PEOPLE WITH TREATMENT-RESISTANT SCHIZOPHRENIA
    Weiner, Elaine
    Ball, M. P.
    Feldman, S.
    Conley, R.
    Kelly, D.
    Gold, J. M.
    McMahon, R. P.
    Buchanan, R. W.
    [J]. SCHIZOPHRENIA BULLETIN, 2009, 35 : 358 - 358
  • [49] Olanzapine versus clozapine in treatment-resistant or treatment-intolerant schizophrenia
    Bitter, I
    Dossenbach, MRK
    Brook, S
    Feldman, PD
    Metcalfe, S
    Gagiano, CA
    Füredi, J
    Bartko, G
    Janka, Z
    Banki, CM
    Kovacs, G
    Breier, A
    [J]. PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY, 2004, 28 (01): : 173 - 180
  • [50] Changes in Brain Glutamate on Switching to Clozapine in Treatment-Resistant Schizophrenia
    McQueen, Grant
    Sendt, Kyra-Verena
    Gillespie, Amy
    Avila, Alessia
    Lally, John
    Vallianatou, Kalliopi
    Chang, Nynn
    Ferreira, Diogo
    Borgan, Faith
    Howes, Oliver D.
    Barker, Gareth J.
    Lythgoe, David J.
    Stone, James M.
    McGuire, Philip
    MacCabe, James H.
    Egerton, Alice
    [J]. SCHIZOPHRENIA BULLETIN, 2021, 47 (03) : 662 - 671