Increasing Drug Resistance in Extensively Drug-Resistant Tuberculosis, South Africa

被引:43
|
作者
Shah, N. Sarita [1 ,2 ,3 ]
Richardson, Jessica [2 ,3 ]
Moodley, Prashini [4 ]
Moodley, Salona [4 ]
Babaria, Palav [2 ,5 ]
Ramtahal, Melissa [4 ]
Heysell, Scott K. [2 ]
Li, Xuan [3 ]
Moll, Anthony P. [2 ,6 ]
Friedland, Gerald [2 ,5 ]
Sturm, A. Willem [4 ]
Gandhi, Neel R. [2 ,3 ]
机构
[1] Albert Einstein Coll Med, Dept Med, Bronx, NY 10467 USA
[2] Tugela Ferry Care & Res Collaborat, Tugela Ferry, South Africa
[3] Montefiore Med Ctr, Bronx, NY 10467 USA
[4] Nelson R Mandela Sch Med, Durban, South Africa
[5] Yale Univ, New Haven, CT USA
[6] Philanjalo Care Ctr, Tugela Ferry, South Africa
关键词
EMERGENCE;
D O I
10.3201/eid1703.101363
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
We expanded second-line tuberculosis (TB) drug susceptibility testing for extensively drug-resistant Mycobacterium tuberculosis isolates from South Africa. Of 19 patients with extensively drug-resistant TB identified during February 2008 April 2009, 13 (68%) had isolates resistant to all 8 drugs tested. This resistance leaves no effective treatment with available drugs in South Africa.
引用
收藏
页码:510 / 513
页数:4
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