Ruthenium-catalyzed ring-opening and ring-closing enyne metathesis

被引：82
|
作者：
Kitamura, T [1 ]
Mori, R [1 ]
机构：
[1] Hokkaido Univ, Grad Sch Pharmaceut Sci, Sapporo, Hokkaido 0600812, Japan
来源：
ORGANIC LETTERS | 2001年 / 3卷 / 08期
关键词：
D O I：
10.1021/ol015606m
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
When a CH2Cl2 solution of an enyne containing the cycloalkene moiety was stirred in the presence of ruthenium-carbene complex (10 mol %) at room temperature under ethylene gas (1 atm), ring-opening and ring closing metathesis occurred to afford cyclized triene. The reaction was carried out under argon gas, and no cyclized product was obtained. Enynes with a terminal alkyne gave good results.
引用
收藏
页码：1161 / 1163
页数：3
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