Genome-Wide Mapping of SNPs in Non-coding RNAs

被引：0

作者：

Ning, Shangwei ^{[1
]}

Zhang, Yunpeng ^{[1
]}

机构：

[1] Harbin Med Univ, Coll Bioinformat Sci & Technol, Harbin, Heilongjiang, Peoples R China

来源：

NON-CODING RNAS IN COMPLEX DISEASES: A BIOINFORMATICS PERSPECTIVE | 2018年 / 1094卷

关键词：

miRNA; lncRNA; Disease; Single nucleotide polymorphisms (SNPs); MICRORNA TARGET SITE; SINGLE-NUCLEOTIDE POLYMORPHISMS; BINDING-SITES; CANCER-RISK; GENE; ASSOCIATION; LONG; DATABASE; VARIANTS; ANNOTATION;

D O I：

10.1007/978-981-13-0719-5_5

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Non-coding RNAs (ncRNAs) are essential players that participate in multiple cellular processes. Cumulative evidence has linked ncRNA-related single nucleotide polymorphisms (SNPs) to various human diseases. However, the knowledge of ncRNA-related SNPs and their potential functional mechanisms in human disease need to be further discovered. Here, we reviewed related studies on functional SNPs in two main types of ncRNA, microRNAs (miRNAs) and long non-coding RNAs (lncRNAs), with a particular focus on these ncRNA-related SNPs as novel risk factor of disease etiology. These studies will gain global insights into the relationship between ncRNAs and their functions.

引用

页码：39 / 48

页数：10

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