A straightforward metal-free synthesis of 2-substituted thiazolines in air

被引：19
|
作者：
Trose, Michael [1 ]
Lazreg, Faima [1 ]
Lesieur, Mathieu [1 ]
Cazin, Catherine S. J. [1 ]
机构：
[1] Univ St Andrews, EaStCHEM, Sch Chem, St Andrews KY16 9ST, Fife, Scotland
来源：
GREEN CHEMISTRY | 2015年 / 17卷 / 05期
关键词：
SOLVENT-FREE CONDITIONS; N-HETEROCYCLIC CARBENE; CHIRAL LIGANDS; 2-THIAZOLINES; COMPLEXES; OXAZOLINES; CYCLODEHYDRATION; IMIDAZOLINES; CATALYSTS; ACID;
D O I：
10.1039/c5gc00286a
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
A base-catalysed procedure for the synthesis of 2-substituted thiazolines from nitriles and cysteamine hydrochloride under solvent-free conditions is presented. This straightforward approach allows high conversion for a broad range of nitriles and an easy isolation of the desired products.
引用
收藏
页码：3090 / 3092
页数：3
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