Recent Advances in Transition-Metal-Catalyzed Synthesis of Coumarins

Coumarin is a privileged scaffold found in a large number of biologically active natural products, pharmaceuticals and agrochemicals, and functionalized coumarins are also widely employed as materials. For this reason, considerable interest has been focused on the development of new protocols to access this heterocyclic moiety in the past few decades. Among the numerous methods developed so far, transition-metal-catalyzed reactions are the most attractive methodologies for the synthesis of coumarins under rather mild reaction conditions. This review provides an overview of the recent developments in this field. 1 Introduction 2 Palladium Catalysis 3 Platinum Catalysis 4 Cobalt Catalysis 5 Copper Catalysis 6 Gold Catalysis 7 Iron Catalysis 8 Nickel Catalysis 9 Rhodium Catalysis 10 Ruthenium Catalysis 11 Zinc Catalysis 12 Conclusion