Clinical Narrative: Autoimmune Hepatitis

被引：21

作者：

Schmeltzer, Paul A. ^{[1
]}

Russo, Mark W. ^{[1
]}

机构：

[1] Carolinas Healthcare, Div Hepatol, Charlotte, NC 28203 USA

来源：

AMERICAN JOURNAL OF GASTROENTEROLOGY | 2018年 / 113卷 / 07期

关键词：

CHRONIC ACTIVE HEPATITIS; INDUCED LIVER-INJURY; AZATHIOPRINE METABOLITES; CORTICOSTEROID-THERAPY; IDIOPATHIC AUTOIMMUNE; PREGNANCY; MANAGEMENT; REMISSION; RITUXIMAB; DISEASE;

D O I：

10.1038/s41395-018-0058-z

中图分类号：

R57 [消化系及腹部疾病];

学科分类号：

摘要：

Autoimmune hepatitis (AIH) is an inflammatory liver disease that is characterized by circulating autoantibodies, hypergammaglobulinemia, and a lymphoplasmocytic infiltration with interface hepatitis on liver biopsy. Treatment with corticosteroids and other immunosuppressive agents is effective and early diagnosis can result in near-normal life expectancy. Untreated patients, however, can progress to cirrhosis and liver failure. The clinical presentation is heterogeneous and may pose diagnostic and therapeutic dilemmas. This case-based review will address the diagnosis and management of this disease, in addition to difficult but commonly encountered clinical scenarios.

引用

页码：951 / 958

页数：8

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