6-amino-9-(carboxymethyl)-2-methoxypurine methyl ester

被引：3

作者：

Sood, G ^{[1
]}

Schwalbe, CH ^{[1
]}

Fraser, W ^{[1
]}

机构：

[1] Aston Univ, Inst Pharmaceut Sci, Birmingham B4 7ET, W Midlands, England

来源：

ACTA CRYSTALLOGRAPHICA SECTION C-CRYSTAL STRUCTURE COMMUNICATIONS | 1998年 / 54卷

关键词：

D O I：

10.1107/S0108270197015795

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

The hydrogenolysis of 6-azido-9-(carboxymethyl)-2-methoxypurine methyl ester, (3), formed in a single step from 2,6-dichloro-9-(carboxymethyl)purine ethyl ester, (2), gave the title compound, C9H11N5O3, (1) The side chain attached at N9 avoids steric hindrance with the heterocycle by emerging almost orthogonally [C8-N9-C10-C11 -104.5(2)degrees] and the amino group at N6 donates intermolecular hydrogen bonds to the ring N1 and ester carbonyl O11 atoms.

引用

页码：659 / 661

页数：3

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