A novel NBD-based pH "on-off" fluorescent probe equipped with the N-phenylpiperazine group for lysosome imaging

被引：11
|
作者：
Ma, Zhao [1 ]
Lin, Yuxing [1 ]
Chen, Hui [1 ]
Du, Lupei [1 ]
Li, Minyong [1 ]
机构：
[1] Shandong Univ, Sch Pharm, Dept Med Chem, Key Lab Chem Biol MOE, Jinan 250012, Shandong, Peoples R China
来源：
RSC ADVANCES | 2016年 / 6卷 / 104期
关键词：
CELLS;
D O I：
10.1039/c6ra16996a
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
A novel PET-based fluorescent probe (LN6) targeting to lysosome was found from the synthesized NBD derivatives. This probe was equipped with the novel lysosome-targeted N-phenylpiperazine group, and could be employed to image lysosome and detect its pH change without any washing steps.
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页码：102773 / 102777
页数：5
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