Systems biology: current status and challenges

被引：18

作者：

Zupanic, Anze ^{[1
]}

Bernstein, Hans C. ^{[2
,3
]}

Heiland, Ines ^{[4
]}

机构：

[1] Natl Inst Biol, Dept Biotechnol & Syst Biol, Vecna Pot 111, Ljubljana 1000, Slovenia

[2] Arctic Univ Norway, UiT, Fac Biosci Fisheries & Econ, Tromso, Norway

[3] Arctic Univ Norway, UiT, Arctic Ctr Sustainable Energy, Tromso, Norway

[4] UiT Arctic Univ Norway, Dept Arctic & Marine Biol, Framstedet 39, N-9037 Tromso, Norway

来源：

CELLULAR AND MOLECULAR LIFE SCIENCES | 2020年 / 77卷 / 03期

关键词：

Systems biology; Mathematical modeling; Metabolic pathway analysis; Network dynamics; Multi-scale modeling;

D O I：

10.1007/s00018-019-03410-z

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

We put together a special issue on current approaches in systems biology with a focus on mathematical modeling of metabolic networks. Mathematical models have increasingly been used to unravel molecular mechanisms of complex dynamic biological processes. We here provide a short introduction into the topics covered in this special issue, highlighting current developments and challenges.

引用

页码：379 / 380

页数：2

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