Systems biology: current status and challenges

被引:17
|
作者
Zupanic, Anze [1 ]
Bernstein, Hans C. [2 ,3 ]
Heiland, Ines [4 ]
机构
[1] Natl Inst Biol, Dept Biotechnol & Syst Biol, Vecna Pot 111, Ljubljana 1000, Slovenia
[2] Arctic Univ Norway, UiT, Fac Biosci Fisheries & Econ, Tromso, Norway
[3] Arctic Univ Norway, UiT, Arctic Ctr Sustainable Energy, Tromso, Norway
[4] UiT Arctic Univ Norway, Dept Arctic & Marine Biol, Framstedet 39, N-9037 Tromso, Norway
关键词
Systems biology; Mathematical modeling; Metabolic pathway analysis; Network dynamics; Multi-scale modeling;
D O I
10.1007/s00018-019-03410-z
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
We put together a special issue on current approaches in systems biology with a focus on mathematical modeling of metabolic networks. Mathematical models have increasingly been used to unravel molecular mechanisms of complex dynamic biological processes. We here provide a short introduction into the topics covered in this special issue, highlighting current developments and challenges.
引用
收藏
页码:379 / 380
页数:2
相关论文
共 50 条
  • [1] Systems biology: current status and challenges
    Anze Zupanic
    Hans C. Bernstein
    Ines Heiland
    Cellular and Molecular Life Sciences, 2020, 77 : 379 - 380
  • [2] Current challenges in systems and network biology
    Ideker, T
    CYTOMETRY PART A, 2004, 59A (01): : 62 - 62
  • [3] Current Challenges in Plant Systems Biology
    Daloso, Danilo de Menezes
    Williams, Thomas C. R.
    ADVANCES IN PLANT OMICS AND SYSTEMS BIOLOGY APPROACHES, 2021, 1346 : 155 - 170
  • [4] Current status of systems biology in Aspergilli
    Andersen, M. R.
    Nielsen, J.
    FUNGAL GENETICS AND BIOLOGY, 2009, 46 : S180 - S190
  • [5] Recent advancements in synthetic biology: Current status and challenges
    Singh, Vijai
    GENE, 2014, 535 (01) : 1 - 11
  • [6] Rodent biology and management: Current status, opinion and challenges in China
    Liu Xiao-hui
    JOURNAL OF INTEGRATIVE AGRICULTURE, 2019, 18 (04) : 830 - 839
  • [7] Rodent biology and management: Current status, opinion and challenges in China
    LIU Xiao-hui
    Journal of Integrative Agriculture, 2019, 18 (04) : 830 - 839
  • [8] TRAUMA SYSTEMS - CURRENT STATUS - FUTURE CHALLENGES
    WEST, JG
    WILLIAMS, MJ
    TRUNKEY, DD
    WOLFERTH, CC
    JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 1988, 259 (24): : 3597 - 3600
  • [9] A ribose world: current status and future challenges of plant RNA biology
    Marquardt, Sebastian
    Manavella, Pablo Andres
    JOURNAL OF EXPERIMENTAL BOTANY, 2023, 74 (07) : 2203 - 2207
  • [10] Biology and conservation of the American White Pelican: Current status and future challenges
    Murphy, EC
    WATERBIRDS, 2005, 28 : 107 - 112