GenomeCons: a web server for manipulating multiple genome sequence alignments and their consensus sequences

被引：3
|
作者：
Sato, Tetsuya [1 ,2 ]
Suyama, Mikita [1 ,2 ]
机构：
[1] Kyushu Univ, Med Inst Bioregulat, Fukuoka 8128582, Japan
[2] Japan Sci & Technol Agcy, CREST, Fukuoka 8128582, Japan
来源：
BIOINFORMATICS | 2015年 / 31卷 / 08期
关键词：
BROWSER;
D O I：
10.1093/bioinformatics/btu803
中图分类号：
Q5 [生物化学];
学科分类号：
071010 ; 081704 ;
摘要：
Genome sequence alignments provide valuable information on many aspects of molecular biological processes. In this study, we developed a web server, GenomeCons, for manipulating multiple genome sequence alignments and their consensus sequences for high-throughput genome sequence analyses. This server facilitates the visual inspection of multiple genome sequence alignments for a set of genomic intervals at a time. This allows the user to examine how these sites are evolutionarily conserved over time for their functional importance. The server also reports consensus sequences for the input genomic intervals, which can be applied to downstream analyses such as the identification of common motifs in the regions determined by ChIP-seq experiments.
引用
收藏
页码：1293 / 1295
页数：3
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