Antioxidant and free radical scavenging activities of Terminalia chebula

被引:1
|
作者
Cheng, HY
Lin, TC
Yu, KH
Yang, CM
Lin, CC [1 ]
机构
[1] Kaohsiung Med Univ, Grad Inst Pharmaceut Sci, Coll Pharm, Kaohsiung 807, Taiwan
[2] Tajen Inst Technol, Dept Pharm, Pingtung 907, Taiwan
[3] Kaohsiung Med Univ, Grad Inst Nat Prod, Coll Pharm, Kaohsiung 807, Taiwan
关键词
Terminalia chebula; antioxidant activity; casuarinin; chebulanin; chebulinic acid; 1,6-di-O-galloyl-beta-D-glucose;
D O I
暂无
中图分类号
R9 [药学];
学科分类号
1007 ;
摘要
Free radicals react with biological molecules and destroy the structure of cells, which eventually causes free-radical induced disease such as cancer, renal failure, aging, etc. In this study, 6 extracts and 4 pure compounds of Terminalia chebula RETZ. were investigated for anti-lipid peroxidation, anti-superoxide radical formation and free radical scavenging activities. The superoxide radical scavenging of the 4 pure compounds was further evaluated using electron spin resonance (ESR) spectrometry. The results showed that all tested extracts and pure compounds of T chebula exhibited antioxidant activity at different magnitudes of potency. The antioxidant activity of each pure compound was derived from different pathways and was suggested to be specific.
引用
收藏
页码:1331 / 1335
页数:5
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