The aim of the present work was to remove organic impurities from water using a reactor with photoactive refill. Application of the photoactive refill solves the problem of the replacement of the reactor or its parts when the photocatalyst activity decreases. In case of photocatalytic activity drop, only the photoactive refill can easily be replaced. Titanium dioxide coating was immobilized on the glass fabric as a thin layer from the alcoholic suspension followed by thermal stabilization. The results of studies revealed that the titania coating shows a high photocatalytic potential for the decomposition of the model organic compounds (azodye Acid Red 18, phenol and methylene blue) in water. The coating exhibits high stability in repeated cycles of water treatment.