An efficient one-pot synthesis of flavones

被引：35

作者：

Chee, Chin Fei ^{[2
]}

Buckle, Michael J. C. ^{[1
]}

Abd Rahman, Noorsaadah ^{[2
]}

机构：

[1] Univ Malaya, Dept Pharm, Kuala Lumpur 50603, Malaysia

[2] Univ Malaya, Dept Chem, Kuala Lumpur 50603, Malaysia

来源：

TETRAHEDRON LETTERS | 2011年 / 52卷 / 24期

关键词：

CHEMICAL-PROPERTIES; HYDROXYFLAVONES;

D O I：

10.1016/j.tetlet.2011.04.022

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Flavones were prepared using a one-pot procedure starting from the corresponding 2'-hydroxyacetophenones. The latter were treated with 3 equiv of aroyl chloride in wet K2CO3/acetone (1% w/w water) to afford a good yield of flavone and a smaller amount of 3-aroylflavone. Evidence was obtained that the reaction proceeds via a triketone intermediate. When the reactants were heated in 1,8-diazabicyclo[5.4.0]undec-7-ene (DBU) and pyridine, the 3-aroylflavone was obtained exclusively. Use of a stoichiometric amount of aroyl chloride afforded only the corresponding flavone. (C) 2011 Elsevier Ltd. All rights reserved.

引用

页码：3120 / 3123

页数：4

共 50 条

[31] Efficient one-pot synthesis of 2-aryldihydrobenzofuran
Pan, CF
Ma, ZX
Yu, J
Zhang, ZH
Hui, AL
Wang, ZY
[J]. SYNLETT, 2005, (12) : 1922 - 1926
[32] Highly efficient one-pot synthesis of dihydropyran heterocycles
Mohamed A.Ameen
Sara M.Motamed
Fathy F.Abdel-latif
[J]. Chinese Chemical Letters, 2014, 25 (02) : 212 - 214
[33] Efficient one-pot synthesis of JM3100
Guillaume, D
Marshall, GR
[J]. SYNTHETIC COMMUNICATIONS, 1998, 28 (15) : 2903 - 2906
[34] An efficient one-pot microwave assisted synthesis of dibenzoazepinones
Deb, Prasant K.
Sharma, Somesh
Borude, Avinash
Singh, Ravi P.
Kumar, Deepak
Reddy, L. Krishnakanth
[J]. TETRAHEDRON LETTERS, 2013, 54 (23) : 2916 - 2919
[35] Alum:An efficient catalyst for one-pot synthesis of α-aminophosphonates
Swapnil S.Sonar
Kiran F.Shelke
Gopal K.Kakade
Bapurao B.Shingate
Murlidhar S.Shingare
[J]. Chinese Chemical Letters, 2009, 20 (09) : 1042 - 1046
[36] Efficient one-pot enzymatic synthesis of dephospho coenzyme A
Sapkota, Krishna
Huang, Faqing
[J]. BIOORGANIC CHEMISTRY, 2018, 76 : 23 - 27
[37] An efficient one-pot synthesis of novel pyrazolophthalazinyl spirooxindoles
Gnanamani Shanthi
Paramasivan T. Perumal
[J]. Journal of Chemical Sciences, 2010, 122 : 415 - 421
[38] Highly efficient one-pot synthesis of dihydropyran heterocycles
Ameen, Mohamed A.
Motamed, Sara M.
Abdel-latif, Fathy F.
[J]. CHINESE CHEMICAL LETTERS, 2014, 25 (02) : 212 - 214
[39] One-Pot synthesis of flavones catalyzed by an Au-mediated covalent organic framework
Yang, Chenghan
Mao, Chunfeng
Deng, Qinghua
Yang, Yong
Zhou, Yuming
Zhang, Yiwei
[J]. JOURNAL OF COLLOID AND INTERFACE SCIENCE, 2023, 642 : 283 - 291
[40] One-pot synthesis
Anon
[J]. Chemical and Engineering News, 2002, 80 (46):

← 1 2 3 4 5 →