How Close Are We in Utilizing Functional Neuroimaging in Routine Clinical Diagnosis of Neuropathic Pain?

被引:9
|
作者
Borsook, David [1 ]
Becerra, Lino [1 ]
机构
[1] Harvard Univ, Sch Med, McLean Hosp, Ctr Pain & Brain,Brain Imaging Ctr, Belmont, MA 02478 USA
关键词
Functional magnetic resonance imaging; fMRI; Biomarker; Personalized medicine; Radiology; Morphometry; Objective measure; Diagnosis; MAGNETIC-RESONANCE-SPECTROSCOPY; PRIMARY SOMATOSENSORY CORTEX; CORTICAL REORGANIZATION; CENTRAL SENSITIZATION; POSTSURGICAL PAIN; RISK-FACTORS; HUMAN BRAIN; ALLODYNIA; REPRESENTATION; HYPERALGESIA;
D O I
10.1007/s11916-011-0187-1
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
As with many disorders affecting the central nervous system, treatment of chronic pain is fraught with difficulties related to specific diagnosis and measures of treatment efficacy. Given the recent advances that brain-imaging techniques have contributed to our understanding of how chronic pain affects multiple aspects of brain function (including sensory, emotional, cognitive, and modulatory), opportunities to use these approaches in the clinic are clearly a focus of research laboratories around the world. The routine application of brain imaging as a clinical marker of disease state or therapeutic (drug) efficacy would significantly enhance the clinical process by providing objective measures for clinicians and patients.
引用
收藏
页码:223 / 229
页数:7
相关论文
共 50 条
  • [21] Differential Diagnosis of Chronic Neuropathic Orofacial Pain: Role of Clinical Neurophysiology
    Jaaskelainen, Satu K.
    JOURNAL OF CLINICAL NEUROPHYSIOLOGY, 2019, 36 (06) : 422 - 429
  • [22] The Diagnosis of Chronic Pelvic Pain: How Can We Detect Urological Pain?
    Jo, Jung Ki
    Kim, Yong Tae
    INTERNATIONAL NEUROUROLOGY JOURNAL, 2022, 26 (02) : 87 - 91
  • [23] The Role of Phytochemicals in Managing Neuropathic Pain: How Much Progress Have We Made?
    Sic, Aleksandar
    Manzar, Aarish
    Knezevic, Nebojsa Nick
    NUTRIENTS, 2024, 16 (24)
  • [24] Thyroid cancer genetics: how close are we to personalizing clinical management?
    Ngeow, Joanne
    Eng, Charis
    PERSONALIZED MEDICINE, 2012, 9 (04) : 355 - 358
  • [25] How to diagnose neuropathic pain? The contribution from clinical examination, pain questionnaires and diagnostic tests
    La Cesa, S.
    Tamburin, S.
    Tugnoli, V.
    Sandrini, G.
    Paolucci, S.
    Lacerenza, M.
    Marchettini, P.
    Cruccu, G.
    Truini, A.
    NEUROLOGICAL SCIENCES, 2015, 36 (12) : 2169 - 2175
  • [26] Functional neuroimaging in the diagnosis of patients with parkinsonism: Update and recommendations for clinical use
    Arbizu, J.
    Luquin, M. R.
    Abella, J.
    de la Fuente-Fernandez, R.
    Fernandez-Torron, R.
    Garcia-Solis, D.
    Garrastachu, P.
    Jimenez-Hoyuela, J. M.
    Llaneza, M.
    Lomena, F.
    Lorenzo-Bosquet, C.
    Marti, M. J.
    Martinez-Castrillo, J. C.
    Mir, P.
    Mitjavila, M.
    Ruiz-Martinez, J.
    Vela, L.
    REVISTA ESPANOLA DE MEDICINA NUCLEAR E IMAGEN MOLECULAR, 2014, 33 (04): : 215 - 226
  • [27] How to diagnose neuropathic pain? The contribution from clinical examination, pain questionnaires and diagnostic tests
    S. La Cesa
    S. Tamburin
    V. Tugnoli
    G. Sandrini
    S. Paolucci
    M. Lacerenza
    P. Marchettini
    G. Cruccu
    A. Truini
    Neurological Sciences, 2015, 36 : 2169 - 2175
  • [28] Developments in pharmacotherapeutic agents for hepatitis B - how close are we to a functional cure?
    Khan, Naoshin
    Almajed, Mohamed Ramzi
    Fitzmaurice, Mary Grace
    Jafri, Syed-Mohammed
    EXPERT OPINION ON PHARMACOTHERAPY, 2023, 24 (09) : 1001 - 1011
  • [29] Functional neuroimaging during altered states of consciousness: how and what do we measure?
    Hirsch, J
    BOUNDARIES OF CONSCIOUSNESS: NEUROBIOLOGY AND NEUROPATHOLOGY, 2005, 150 : 25 - 43
  • [30] Efficacy and safety of pregabalin in treatment refractory patients with various neuropathic pain entities in clinical routine
    Freynhagen, R.
    Grond, S.
    Schuepfer, G.
    Hagebeuker, A.
    Schmelz, M.
    Ziegler, D.
    Von Giesen, H. -J.
    Junker, U.
    Wagner, K. J.
    Konrad, C.
    INTERNATIONAL JOURNAL OF CLINICAL PRACTICE, 2007, 61 (12) : 1989 - 1996