A simple synthesis of the lamellarin analogues from 3-nitro-2-trifluoromethyl-2H-chromenes and 1-benzyl-3,4-dihydroisoquinolines

被引：9

作者：

Korotaev, Vladislav Yu ^{[1
]}

Sosnovskikh, Vyacheslav Ya ^{[1
]}

Yasnova, Evgeniya S. ^{[1
]}

Barkov, Alexey Yu ^{[1
]}

Shklyaev, Yurii V. ^{[2
]}

机构：

[1] AM Gorky Ural State Univ, Dept Chem, Ekaterinburg 620083, Russia

[2] Russian Acad Sci, Ural Branch, Inst Tech Chem, Perm 614600, Russia

来源：

MENDELEEV COMMUNICATIONS | 2010年 / 20卷 / 06期

关键词：

STEREOSELECTIVE-SYNTHESIS; N-NUCLEOPHILES; C-NUCLEOPHILES; S-NUCLEOPHILES; 3-NITRO-2-TRIHALOMETHYL-2H-CHROMENES;

D O I：

10.1016/j.mencom.2010.11.006

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

The basic structural framework of lamellarin alkaloids, 8,9-dihydro-6H-chromeno[4',3':4,5]pyrrolo[2,1-a]isoquinoline derivatives, was accessed in good yields by the Grob reaction between 3-nitro-2-trifluoromethyl-2H-chromenes and dihydropapaverine or drotaverine in refluxing isobutanol.

引用

页码：321 / 322

页数：2

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