A simple synthesis of the lamellarin analogues from 3-nitro-2-trifluoromethyl-2H-chromenes and 1-benzyl-3,4-dihydroisoquinolines

被引：9
|
作者：
Korotaev, Vladislav Yu [1 ]
Sosnovskikh, Vyacheslav Ya [1 ]
Yasnova, Evgeniya S. [1 ]
Barkov, Alexey Yu [1 ]
Shklyaev, Yurii V. [2 ]
机构：
[1] AM Gorky Ural State Univ, Dept Chem, Ekaterinburg 620083, Russia
[2] Russian Acad Sci, Ural Branch, Inst Tech Chem, Perm 614600, Russia
来源：
MENDELEEV COMMUNICATIONS | 2010年 / 20卷 / 06期
关键词：
STEREOSELECTIVE-SYNTHESIS; N-NUCLEOPHILES; C-NUCLEOPHILES; S-NUCLEOPHILES; 3-NITRO-2-TRIHALOMETHYL-2H-CHROMENES;
D O I：
10.1016/j.mencom.2010.11.006
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
The basic structural framework of lamellarin alkaloids, 8,9-dihydro-6H-chromeno[4',3':4,5]pyrrolo[2,1-a]isoquinoline derivatives, was accessed in good yields by the Grob reaction between 3-nitro-2-trifluoromethyl-2H-chromenes and dihydropapaverine or drotaverine in refluxing isobutanol.
引用
收藏
页码：321 / 322
页数：2
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