Broadband superluminescent diode-based ultrahigh resolution optical coherence tomography for ophthalmic imaging

被引：33
|
作者：
Zhu, Dexi [2 ]
Shen, Meixiao
Jiang, Hong
Li, Ming [2 ]
Wang, Michael R. [3 ]
Wang, Yuhong [2 ]
Ge, Lili [2 ]
Qu, Jia [2 ]
Wang, Jianhua [1 ]
机构：
[1] Univ Miami, Miller Sch Med, Bascom Palmer Eye Inst, Dept Ophthalmol, Miami, FL 33136 USA
[2] Wenzhou Med Coll, Sch Ophthalmol & Optometry, Wenzhou 325000, Zhejiang, Peoples R China
[3] Univ Miami, Dept Elect & Comp Engn, Miami, FL 33136 USA
来源：
JOURNAL OF BIOMEDICAL OPTICS | 2011年 / 16卷 / 12期
关键词：
optical coherence tomography; ophthalmic imaging; HIGH-SPEED; DOMAIN; OCT;
D O I：
10.1117/1.3660314
中图分类号：
Q5 [生物化学];
学科分类号：
071010 ; 081704 ;
摘要：
Spectral domain optical coherence tomography (SD-OCT) with ultrahigh resolution can be used to measure precise structures in the context of ophthalmic imaging. We designed an ultrahigh resolution SD-OCT system based on broadband superluminescent diode (SLD) as the light source. An axial resolution of 2.2 mu m in tissue, a scan depth of 1.48 mm, and a high sensitivity of 93 dB were achieved by the spectrometer designed. The ultrahigh-resolution SD-OCT system was employed to image the human cornea and retina with a cross-section image of 2048 x 2048 pixels. Our research demonstrated that ultrahigh -resolution SD-OCT can be achieved using broadband SLD in a simple way. (C) 2011 Society of Photo-Optical Instrumentation Engineers (SPIE). [DOI: 10.1117/1.3660314]
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页数：7
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