Serum omentin-1 levels are inversely associated with the presence and severity of coronary artery disease in patients with metabolic syndrome

被引：89

作者：

Shang, Fu-Jun ^{[1
]}

Wang, Jie-Pin ^{[2
]}

Liu, Xiong-Tao ^{[1
]}

Zheng, Qiang-Sun ^{[1
]}

Xue, Yu-Sheng ^{[1
]}

Wang, Bin ^{[1
]}

Zhao, Lian-You ^{[1
]}

机构：

[1] Fourth Mil Med Univ, Dept Cardiol, Tangdu Hosp, Xian 710038, Shaanxi, Peoples R China

[2] Fourth Mil Med Univ, Dept Pharm, Tangdu Hosp, Xian 710038, Shaanxi, Peoples R China

来源：

BIOMARKERS | 2011年 / 16卷 / 08期

关键词：

Adipokines; biomarker; cardiometabolic syndrome; coronary atherosclerosis index; CHOLESTEROL; INFLAMMATION; ADIPOKINES; MORTALITY;

D O I：

10.3109/1354750X.2011.622789

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

Context: Omentin-1, an adipokine secreted from visceral adipose tissue, has been reported to be associated with coronary artery disease (CAD) and metabolic disorders. Objective: To clarify the relationship between serum omentin-1 levels and the presence and severity of CAD in patients with metabolic syndrome (MetS). Methods: We measured serum omentin-1 levels in 175 consecutive patients with MetS and in 46 controls. Results: Serum omentin-1 levels are inversely associated with the presence and angiographic severity of CAD in MetS patients. Conclusions: Serum omentin-1 might be a potential biomarker to predict the development and progression of CAD in MetS patients.

引用

页码：657 / 662

页数：6

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