INHIBITION OF HISTONE DEACETYLASE 6 ACTIVITY PROVIDES PROTECTION AGAINST ATHEROGENESIS: A ROLE FOR HDAC6 NEDDYLATION

被引:1
|
作者
Pandey, Deepesh [1 ]
Nomura, Yohei [1 ]
Rossberg, Max [1 ]
Bhatta, Anil [1 ]
Romer, Lew [1 ]
Berkowitz, Dan [1 ]
机构
[1] Johns Hopkins Univ, Sch Med, Baltimore, MD 21218 USA
关键词
Vascular biology; endothelial dysfunction; atherosclerosis; epigenetics; histone deacetylases;
D O I
10.1097/01.hjh.0000548167.75434.d6
中图分类号
R6 [外科学];
学科分类号
1002 ; 100210 ;
摘要
A5942
引用
收藏
页码:E44 / E45
页数:2
相关论文
共 50 条
  • [21] Hdac6: A Novel Histone Deacetylase Implicated In Pulmonary Arterial Hypertension
    Boucherat, O.
    Chabot, S.
    Paulin, R.
    Trinh, I.
    Bourgeois, A.
    Potus, F.
    Lampron, M-C
    Lambert, C.
    Breuils-Bonnet, S.
    Paradis, R.
    Goncharova, E.
    Provencher, S.
    Bonnet, S.
    [J]. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 2017, 195
  • [22] Regulation of microtubule dynamics by inhibition of the tubulin deacetylase HDAC6
    Zilberman, Yuliya
    Ballestrem, Christoph
    Carramusa, Letizia
    Mazitschek, Ralph
    Khochbin, Saadi
    Bershadsky, Alexander
    [J]. JOURNAL OF CELL SCIENCE, 2009, 122 (19) : 3531 - 3541
  • [23] Role of Histone Deacetylase 6 and Histone Deacetylase 6 Inhibition in Colorectal Cancer
    Vuletic, Ana
    Martinovic, Katarina Mirjacic
    Spasic, Jelena
    [J]. PHARMACEUTICS, 2024, 16 (01)
  • [24] Inhibition of HDAC6, a Microtubule Deacetylase, Increases Microtubule Stability
    Asthana, J.
    Mohan, R.
    Panda, D.
    [J]. MOLECULAR BIOLOGY OF THE CELL, 2011, 22
  • [25] Inhibition of Histone Deacetylase 6 (HDAC6) as a therapeutic strategy for Alzheimer's disease: A review (2010-2020)
    Li, Yunheng
    Sang, Shenghu
    Ren, Weijie
    Pei, Yuqiong
    Bian, Yaoyao
    Chen, Yao
    Sun, Haopeng
    [J]. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2021, 226
  • [26] Selective inhibition of histone deacetylase 6 (HDAC6) induces DNA damage and sensitizes transformed cells to anticancer agents
    Namdar, Mandana
    Perez, Gisela
    Ngo, Lang
    Marks, Paul A.
    [J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2010, 107 (46) : 20003 - 20008
  • [27] Structural Basis of Catalysis and Inhibition of HDAC6 CD1, the Enigmatic Catalytic Domain of Histone Deacetylase 6
    Osko, Jeremy D.
    Christianson, David W.
    [J]. BIOCHEMISTRY, 2019, 58 (49) : 4912 - 4924
  • [28] Inhibition of deacetylase activity of Hdac6 causes antidepressant-like behavior in mice
    Fukada, Masahide
    Hanai, Atsuko
    Aoki, Eiko
    Takeshima, Kyoko
    Nakayama, Atsuo
    Kawaguchi, Yoshiharu
    [J]. NEUROSCIENCE RESEARCH, 2011, 71 : E301 - E301
  • [29] Histone deacetylase 6 (HDAC6) is an essential factor for oocyte maturation and asymmetric division in mice
    Dongjie Zhou
    Yun-Jung Choi
    Jin-Hoi Kim
    [J]. Scientific Reports, 7
  • [30] Histone Deacetylase 6 (HDAC6) Regulates Gene Transcription and Enucleation during Erythroid Differentiation
    Li, Xuehui
    Yang, Yurong
    Lu, Jianrong
    McKinsey, Timothy
    Ji, Peng
    Qiu, Yi
    [J]. BLOOD, 2014, 124 (21)