Syngeneic graft-versus-host disease: a report of two cases and literature review

被引:11
|
作者
Latif, T
Pohlman, B
Kalaycio, M
Sobecks, R
Hsi, ED
Andresen, S
Bolwell, BJ
机构
[1] Cleveland Clin Fdn, Dept Clin Pathol, Cleveland, OH 44195 USA
[2] Taussig Canc Ctr, Dept Hematol & Med Oncol, Cleveland, OH USA
关键词
graft-versus-host disease (GVHD); syngeneic graft-versus-host disease (SGVHD); immunosuppression;
D O I
10.1038/sj.bmt.1704171
中图分类号
Q6 [生物物理学];
学科分类号
071011 ;
摘要
Rappeport et al first reported the clinical syndrome of graft-versus-host disease (GVHD) in syngeneic bone marrow transplant patients. Recently, there have been more reports of a GVHD-like syndrome in syngeneic bone marrow transplant patients (SGVHD) that may result in significant clinical morbidity. A total of 17 cases of SGVHD in syngeneic bone marrow transplant patients have been reported to date in the medical literature. The current report reviews these cases and presents two additional cases of severe SGVHD that have occurred at our institution.
引用
收藏
页码:535 / 539
页数:5
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