Foregut duplication cysts in siblings: A case report

Enteric duplication cysts are rare congenital anomalies that result from heterotrophic rests of foregut-derived epithelium in the head, neck, thorax or abdomen. Typically, foregut duplication cysts of the head and neck are diagnosed in asymptomatic children. No single embryologic process has been identified to explain causation. In this case, we report a case of two siblings with foregut duplication cysts-one cyst occurring in the floor of mouth and the other occurring in the thorax as an esophageal duplication. To our knowledge, this is the first report of such an event in the literature. This case raises the question of a possibly inherited foregut cyst versus a spontaneous occurrence in first degree relatives. (C) 2010 Elsevier Ireland Ltd. All rights reserved.