Transition metal-free steric controlled one-pot synthesis of highly substituted N-amino 1,2,3-triazole derivatives via diazo transfer reaction from β-keto esters

被引：11
|
作者：
Nagarajan, Rajendran [1 ]
Jayashankaran, Jayadevan [2 ]
Emmanuvel, Lourdusamy [1 ]
机构：
[1] Karunya Univ, Sch Sci & Humanities, Dept Chem, Coimbatore 641114, Tamil Nadu, India
[2] Syngene Int Ltd, Biocon Pk,Plot 2&3,Bommasandra Ind Estate Phase 4, Bangalore 560099, Karnataka, India
来源：
TETRAHEDRON LETTERS | 2016年 / 57卷 / 24期
关键词：
N-Amino 1,2,3-triazole; Diazo transfer; Metal free reaction; One-pot synthesis; PHASE SYNTHESIS; OXIME ETHERS; CHEMISTRY; TRIAZOLE;
D O I：
10.1016/j.tetlet.2016.04.112
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
An efficient, simple protocol for the one-pot synthesis of N-amino 1,2,3-triazole from beta-keto esters has been described. This method involves diazo transfer reaction into in situ generated hydrazones using imidazole sulfonyl azide as the nitrogen source. This protocol does not involve any transition metal and can be regarded as a general method for the synthesis of N-amino 1,2,3-triazole from hydrazones. (C) 2016 Elsevier Ltd. All rights reserved.
引用
收藏
页码：2612 / 2615
页数：4
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