N-Arylation of carbazole by microwave-assisted ligand-free catalytic CuI reaction

被引：41

作者：

Kwon, Jae Kwan ^{[1
]}

Cho, Joong Hyun ^{[1
]}

Ryu, Young-Sil ^{[1
]}

Oh, Se Hwan ^{[1
]}

Yum, Eul Kgun ^{[1
]}

机构：

[1] Chungnam Natl Univ, Dept Chem, Taejon 305764, South Korea

来源：

TETRAHEDRON | 2011年 / 67卷 / 26期

关键词：

Carbazole; Microwave; N-Arylation; Catalytic; CuI; NITROGEN-CONTAINING HETEROCYCLES; ARYL HALIDES; COUPLING REACTIONS; FACILE SYNTHESIS; HETEROANNULATION; EFFICIENT; INDOLES; DERIVATIVES; ANNULATION;

D O I：

10.1016/j.tet.2011.05.022

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

N-Arylation of carbazole has been achieved in high yields within 1 h using a microwave-assisted catalytic CuI reaction with no organic ligand. The N-arylation can be performed by various arylhalides, such as phenyl, pyridine, thiophene, and thiazole moieties. Specifically, N-arylated bromocarbazoles were converted into useful synthetic intermediates for functionalized carbazole materials. (C) 2011 Elsevier Ltd. All rights reserved.

引用

页码：4820 / 4825

页数：6

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