Efficient Ligand-Free, Copper-Catalyzed N-Arylation of Sulfonamides

被引：29
|
作者：
Teo, Yong-Chua [1 ]
Yong, Fui-Fong [1 ]
机构：
[1] Nanyang Technol Univ, Natl Inst Educ, Singapore 637616, Singapore
来源：
SYNLETT | 2011年 / 06期
关键词：
ligand-free; copper; sulfonamides; N-arylation; CROSS-COUPLING REACTIONS; C-N; ARYL IODIDES; BOND FORMATION; AMINO-ACID; ROOM-TEMPERATURE; BROMIDES; AMIDES; HALIDES; OXIDE;
D O I：
10.1055/s-0030-1259925
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
An efficient and convenient protocol has been developed for the N-arylation of sulfonamides with differently substituted aryl iodides using ligand-free copper iodide to afford the arylated products in good to excellent yields (up to 91%).
引用
收藏
页码：837 / 843
页数：7
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