Filifactor alocis - a new emerging periodontal pathogen

被引：79
|
作者：
Aruni, A. Wilson [1 ]
Mishra, Arunima [1 ]
Dou, Yuetan [1 ]
Chioma, Ozioma [1 ]
Hamilton, Brittany N. [1 ]
Fletcher, Hansel M. [1 ,2 ]
机构：
[1] Loma Linda Univ, Sch Med, Div Microbiol & Mol Genet, Loma Linda, CA 92354 USA
[2] Kyung Hee Univ, Inst Oral Biol, Seoul, South Korea
来源：
MICROBES AND INFECTION | 2015年 / 17卷 / 07期
关键词：
Filifactor alocis; Polymicrobial infection; Periodontitis; Community dynamics; CRISPR-CAS SYSTEMS; FAILED ENDODONTIC TREATMENT; PORPHYROMONAS-GINGIVALIS; EPITHELIAL-CELLS; ARGININE DEIMINASE; AGGRESSIVE PERIODONTITIS; RHEUMATOID-ARTHRITIS; FUSOBACTERIUM; INFECTIONS; VIRULENCE;
D O I：
10.1016/j.micinf.2015.03.011
中图分类号：
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号：
100102 ;
摘要：
Filifactor alocis, a previously unrecognized Gram-positive anaerobic rod, is now considered a new emerging pathogen that may play a significant role in periodontal disease. F. alocis' unique characteristics and variations at the molecular level that may be responsible for the functional changes required to mediate the pathogenic process are discussed. (C) 2015 Published by Elsevier Masson SAS on behalf of Institut Pasteur.
引用
收藏
页码：517 / 530
页数：14
相关论文
共 50 条
  • [21] Characterization and immunostimulatory activity of extracellular vesicles from Filifactor alocis
    Kim, Hyun Young
    Lim, Younggap
    An, Sun-Jin
    Choi, Bong-Kyu
    MOLECULAR ORAL MICROBIOLOGY, 2020, 35 (01) : 1 - 9
  • [22] Filifactor alocis modulates human neutrophil antimicrobial functional responses
    Edmisson, Jacob S.
    Tian, Shifu
    Armstrong, Cortney L.
    Vashishta, Aruna
    Klaes, Christopher K.
    Miralda, Irina
    Jimenez-Flores, Emeri
    Le, Junyi
    Wang, Qian
    Lamont, Richard J.
    Uriarte, Silvia M.
    CELLULAR MICROBIOLOGY, 2018, 20 (06)
  • [23] Prevalence of the oral pathogen Filifactor alocis and its FtxA toxin related to clinical parameters and presence of Aggregatibacter actinomycetemcomitans
    Razooqi, Zeinab
    Khzam, Nabil
    L'Hostis, Mahina
    Belibasakis, Georgios N.
    Johansson, Anders
    Oscarsson, Jan
    FRONTIERS IN CELLULAR AND INFECTION MICROBIOLOGY, 2025, 14
  • [24] Investigation of Filifactor alocis in primary and in secondary endodontic infections: A molecular study
    Gomes, Brenda P. F. A.
    Louzada, Lidiane M.
    Almeida-Gomes, Rebecca F.
    Pinheiro, Ericka T.
    Sousa, Ezilmara L. R.
    Jacinto, Rogerio C.
    Arruda-Vasconcelos, Rodrigo
    ARCHIVES OF ORAL BIOLOGY, 2020, 118
  • [25] Proteomic Characterization of the Oral Pathogen Filifactor alocis Reveals Key Inter-Protein Interactions of Its RTX Toxin: FtxA
    Bao, Kai
    Claesson, Rolf
    Gehrig, Peter
    Grossmann, Jonas
    Oscarsson, Jan
    Belibasakis, Georgios N.
    PATHOGENS, 2022, 11 (05):
  • [26] Regulation of Cyclooxygenase 2 by Filifactor alocis in Fibroblastic and Monocytic Cells
    Nokhbehsaim, Marjan
    Nogueira, Andressa V. B.
    Nietzsche, Sandor
    Eick, Sigrun
    Deschner, James
    MEDIATORS OF INFLAMMATION, 2020, 2020
  • [27] Characterization of thioredoxin-thioredoxin reductase system in Filifactor alocis
    Mishra, Arunima
    Dou, Yuetan
    Fletcher, Hansel M.
    MOLECULAR ORAL MICROBIOLOGY, 2025, 40 (01) : 50 - 63
  • [28] Proteome Analysis of Coinfection of Epithelial Cells with Filifactor alocis and Porphyromonas gingivalis Shows Modulation of Pathogen and Host Regulatory Pathways
    Aruni, A. Wilson
    Zhang, Kangling
    Dou, Yuetan
    Fletcher, Hansel
    INFECTION AND IMMUNITY, 2014, 82 (08) : 3261 - 3274
  • [29] Filifactor alocis: The Newly Discovered Kid on the Block with Special Talents
    Aruni, W.
    Chioma, O.
    Fletcher, H. M.
    JOURNAL OF DENTAL RESEARCH, 2014, 93 (08) : 725 - 732
  • [30] Virulence of Filifactor alocis lipoteichoic acid on human gingival fibroblast
    Yoo, Hyun-Jun
    Lee, Sung-Hoon
    ARCHIVES OF ORAL BIOLOGY, 2022, 135
12345