EPR Studies of DOPA-Melanin Complexes with Fe(III)

被引：26
|
作者：
Zdybel, Magdalena [1 ]
Chodurek, Ewa [2 ]
Pilawa, Barbara [1 ]
机构：
[1] Med Univ Silesia, Dept Biophys, Sch Pharm, PL-41200 Sosnowiec, Poland
[2] Med Univ Silesia, Dept Biopharm, Sch Pharm, PL-41200 Sosnowiec, Poland
来源：
APPLIED MAGNETIC RESONANCE | 2011年 / 40卷 / 01期
关键词：
ELECTRON-SPIN-RESONANCE; FREE-RADICALS; BINDING-SITES; PARAMAGNETIC CENTERS; SYNTHETIC MELANIN; METAL-BINDING; NEUROMELANIN; EUMELANINS; OXIDATION; CU2+;
D O I：
10.1007/s00723-010-0187-z
中图分类号：
O64 [物理化学（理论化学）、化学物理学]; O56 [分子物理学、原子物理学];
学科分类号：
070203 ; 070304 ; 081704 ; 1406 ;
摘要：
Paramagnetic centers in 3,4-dihydroxyphenylalanine-melanin and its complexes with Fe(III) were examined by electron paramagnetic resonance (EPR) spectroscopy. Paramagnetic centers of melanin play an important role in detoxification of environment and they reveal high activity in binding of metal ions. Two different signals were observed in EPR spectra: lines of o-semiquinone free radicals and lines of paramagnetic Fe(III). Amplitudes of EPR lines of both free radicals and iron ions decrease with increasing Fe(III) content in melanin-metal ion complexes. Free radical concentrations in the melanin samples, g-factors, amplitudes and line widths of EPR spectra were determined. It was stated that fast spin-lattice relaxation processes exist in both free radical system and paramagnetic iron ions in melanin complexes.
引用
收藏
页码：113 / 123
页数：11
相关论文
共 50 条
  • [1] EPR Studies of DOPA–Melanin Complexes with Fe(III)
    Magdalena Zdybel
    Ewa Chodurek
    Barbara Pilawa
    Applied Magnetic Resonance, 2011, 40 : 113 - 123
  • [2] Influence of Microwave Power on EPR Signal of Melanin Radical and Copper(II) Ions in DOPA-Melanin Complexes
    Najder-Kozdrowska, L.
    Pilawa, B.
    Wieckowski, A. B.
    Buszman, E.
    Wrzesniok, D.
    ACTA PHYSICA POLONICA A, 2013, 124 (01) : 112 - 114
  • [3] EPR Studies of DOPA-Melanin Complexes with Netilmicin and Cu(II) at Temperatures in the Range of 105-300 K
    Zdybel, Magdalena
    Pilawa, Barbara
    Buszman, Ewa
    Wrzesniok, Dorota
    Krzyminiewski, Ryszard
    Kruczynski, Zdzislaw
    APPLIED MAGNETIC RESONANCE, 2012, 43 (03) : 341 - 351
  • [4] Electron paramagnetic resonance (EPR) study of DOPA-melanin complexes with kanamycin and copper(II) ions
    Najder-Kozdrowska, Lidia
    Pilawa, Barbara
    Buszman, Ewa
    Wrzesniok, Dorota
    Wieckowski, Andrzej B.
    SPECTROSCOPY-BIOMEDICAL APPLICATIONS, 2011, 25 (3-4): : 197 - 205
  • [5] EPR examination of free radical properties of DOPA-melanin complexes with ciprofloxacin, lomefloxacin, norfloxacin and sparfloxacin
    Beberok, Artur
    Buszman, Ewa
    Zdybel, Magdalena
    Pilawa, Barbara
    Wrzesniok, Dorota
    CHEMICAL PHYSICS LETTERS, 2010, 497 (1-3) : 115 - 122
  • [6] Application of EPR spectroscopy to examination of gentamicin and kanamycin binding to DOPA-melanin
    B. Pilawa
    E. Buszman
    D. Wrześniok
    M. Latocha
    T. Wilczok
    Applied Magnetic Resonance, 2002, 23 : 181 - 192
  • [7] RADICAL PRODUCTION DURING TYROSINASE REACTION, DOPA-MELANIN FORMATION, AND PHOTOIRRADIATION OF DOPA-MELANIN
    TOMITA, Y
    HARIU, A
    KATO, C
    SEIJI, M
    JOURNAL OF INVESTIGATIVE DERMATOLOGY, 1984, 82 (06) : 573 - 576
  • [8] REINVESTIGATION ON THE FORMATION OF DOPA-MELANIN
    STRAVS, L
    WYLER, H
    YALE JOURNAL OF BIOLOGY AND MEDICINE, 1984, 57 (03): : 420 - 420
  • [9] Application of EPR spectroscopy to examination of gentamicin and kanamycin binding to DOPA-melanin
    Pilawa, B
    Buszman, E
    Wrzesniok, D
    Latocha, M
    Wilczok, T
    APPLIED MAGNETIC RESONANCE, 2002, 23 (02) : 181 - 192
  • [10] PHOTOINDUCED DESTRUCTION OF DOPA-MELANIN
    KORZHOVA, LP
    FROLOVA, EV
    ROMAKOV, YA
    KUZNETSOVA, NA
    BIOCHEMISTRY-MOSCOW, 1989, 54 (06) : 805 - 810
12345