Determination of the diffusion coefficient of rivanol in dentin of a human tooth in vitro

被引：0
|
作者：
Selifonov, A. A. [1 ,2 ]
Tuchin, V. V. [1 ,3 ,4 ]
机构：
[1] Saratov NG Chernyshevskii State Univ, Dept Opt & Biophoton, Saratov 410012, Russia
[2] Saratov State Med Univ, Saratov 410012, Russia
[3] RAS, Inst Precis Mech & Control, Lab Laser Diagnost Tech & Living Syst, Saratov 410028, Russia
[4] Tomsk State Univ, Interdisciplinary Lab Biophoton, Tomsk 634050, Russia
来源：
BIOMEDICAL SPECTROSCOPY, MICROSCOPY, AND IMAGING | 2020年 / 11359卷
基金：
俄罗斯基础研究基金会;
关键词：
optical method; diffusion coefficient; rivanol; diffuse reflection spectroscopy; dentin; PHOTODYNAMIC THERAPY; ENTEROCOCCUS-FAECALIS; BIOFILMS;
D O I：
10.1117/12.2556085
中图分类号：
TH742 [显微镜];
学科分类号：
摘要：
In the work, the effective diffusion coefficient of an aqueous solution of the pharmaceutical preparation rivanol in slices of human tooth dentin was experimentally determined using the method of reflection spectroscopy. Within the framework of the free diffusion model, in calculations using the second Fick law and the Bouguer-Lambert-Beer law for the optical model, the effective diffusion coefficient of the photosensitizer was calculated, which turned out to be equal on average (2.27 +/- 0.32).10(-6) cm(2)/s (n = 10).
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页数：7
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