Chemoenzymatic approaches to the montanine alkaloids: A total synthesis of (+)-brunsvigine

被引：56
|
作者：
Banwell, Martin G. [1 ]
Kokas, Okanya J. [1 ]
Willis, Anthony C. [1 ]
机构：
[1] Australian Natl Univ, Inst Adv Studies, Res Sch Chem, Canberra, ACT 0200, Australia
来源：
ORGANIC LETTERS | 2007年 / 9卷 / 18期
关键词：
D O I：
10.1021/ol071344y
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
The readily available and enzymatically derived cis-1,2-dihydrocatechols 3a and 3b have been elaborated over 17 steps, including a novel radical addition/elimination sequence, into the enantiomer, (+)-1, of the montanine alkaloid brunsvigine [(-)-1].
引用
收藏
页码：3503 / 3506
页数：4
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