In a phase II trial of the experimental MEK inhibitor selumetinib (AZD6244), women who had failed 3 or more rounds of chemotherapy had 81% disease control and a median progression-free survival of 11.3 months.
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Massachusetts Gen Hosp, Dept Obstet & Gynecol, Vincent Ctr Reprod Biol, Boston, MA 02114 USA
Harvard Univ, Sch Med, Boston, MA USAMassachusetts Gen Hosp, Dept Obstet & Gynecol, Vincent Ctr Reprod Biol, Boston, MA 02114 USA
Groeneweg, Jolijn W.
Foster, Rosemary
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Massachusetts Gen Hosp, Dept Obstet & Gynecol, Vincent Ctr Reprod Biol, Boston, MA 02114 USA
Harvard Univ, Sch Med, Boston, MA USA
Massachusetts Gen Hosp, Dept Obstet & Gynecol, Div Gynecol Oncol, Boston, MA 02114 USAMassachusetts Gen Hosp, Dept Obstet & Gynecol, Vincent Ctr Reprod Biol, Boston, MA 02114 USA
Foster, Rosemary
Growdon, Whitfield B.
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Massachusetts Gen Hosp, Dept Obstet & Gynecol, Vincent Ctr Reprod Biol, Boston, MA 02114 USA
Harvard Univ, Sch Med, Boston, MA USA
Massachusetts Gen Hosp, Dept Obstet & Gynecol, Div Gynecol Oncol, Boston, MA 02114 USAMassachusetts Gen Hosp, Dept Obstet & Gynecol, Vincent Ctr Reprod Biol, Boston, MA 02114 USA
Growdon, Whitfield B.
Verheijen, Rene H. M.
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Univ Med Ctr Utrecht, Dept Gynecol Oncol, Div Woman & Baby, Utrecht, NetherlandsMassachusetts Gen Hosp, Dept Obstet & Gynecol, Vincent Ctr Reprod Biol, Boston, MA 02114 USA
Verheijen, Rene H. M.
Rueda, Bo R.
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Massachusetts Gen Hosp, Dept Obstet & Gynecol, Vincent Ctr Reprod Biol, Boston, MA 02114 USA
Harvard Univ, Sch Med, Boston, MA USA
Massachusetts Gen Hosp, Dept Obstet & Gynecol, Div Gynecol Oncol, Boston, MA 02114 USAMassachusetts Gen Hosp, Dept Obstet & Gynecol, Vincent Ctr Reprod Biol, Boston, MA 02114 USA
机构:
Mem Sloan Kettering Canc Ctr, Dept Med, Gynecol Med Oncol Serv, New York, NY USA
Mem Sloan Kettering Canc Ctr, Dept Med, Gynecol Med Oncol Serv, New York, NY 10065 USAMem Sloan Kettering Canc Ctr, Dept Med, Gynecol Med Oncol Serv, New York, NY USA
Grisham, Rachel N.
Manning-Geist, Beryl L.
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Mem Sloan Kettering Canc Ctr, Dept Surg, Gynecol Serv, New York, NY USAMem Sloan Kettering Canc Ctr, Dept Med, Gynecol Med Oncol Serv, New York, NY USA
Manning-Geist, Beryl L.
Chui, M. Herman
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Mem Sloan Kettering Canc Ctr, Dept Pathol & Lab Med, New York, NY USAMem Sloan Kettering Canc Ctr, Dept Med, Gynecol Med Oncol Serv, New York, NY USA