P-glycoprotein at the blood-brain barrier and analysis of drug transport with positron-emission tomography

被引:0
|
作者
Hendrikse, NH
Bart, J
de Vries, EGE
Groen, HJM
van der Graaf, WTA
Vaalburg, W
机构
[1] Univ Groningen Hosp, PET Ctr, NL-9700 RB Groningen, Netherlands
[2] Univ Groningen Hosp, Dept Med Oncol, Groningen, Netherlands
[3] Univ Groningen Hosp, Dept Pulm Dis, Groningen, Netherlands
关键词
D O I
暂无
中图分类号
R9 [药学];
学科分类号
1007 ;
摘要
引用
收藏
页码:48S / 54S
页数:7
相关论文
共 50 条
  • [21] Factors Governing P-Glycoprotein-Mediated Drug-Drug Interactions at the Blood-Brain Barrier Measured with Positron Emission Tomography
    Wanek, Thomas
    Roemermann, Kerstin
    Mairinger, Severin
    Stanek, Johann
    Sauberer, Michael
    Filip, Thomas
    Traxl, Alexander
    Kuntner, Claudia
    Pahnke, Jens
    Bauer, Florian
    Erker, Thomas
    Loescher, Wolfgang
    Mueller, Markus
    Langer, Oliver
    MOLECULAR PHARMACEUTICS, 2015, 12 (09) : 3214 - 3225
  • [22] Inhibition of P-glycoprotein:: Rapid assessment of its implication in blood-brain barrier integrity and drug transport to the brain by an in vitro model of the blood-brain barrier
    Fenart, L
    Buée-Scherrer, V
    Descamps, L
    Duhem, C
    Poullain, MG
    Cecchelli, R
    Dehouck, MP
    PHARMACEUTICAL RESEARCH, 1998, 15 (07) : 993 - 1000
  • [23] Inhibition of P-Glycoprotein: Rapid Assessment of Its Implication in Blood-Brain Barrier Integrity and Drug Transport to the Brain by an In Vitro Model of the Blood-Brain Barrier
    Laurence Fenart
    Valeric Buée-Scherrer
    Laurence Descamps
    Christian Duhem
    Marie-Gwenaëlle Poullain
    Roméo Cecchelli
    Marie-Pierre Dehouck
    Pharmaceutical Research, 1998, 15 : 993 - 1000
  • [24] A Novel Positron Emission Tomography Imaging Protocol Identifies Seizure-Induced Regional Overactivity of P-Glycoprotein at the Blood-Brain Barrier
    Bankstahl, Jens P.
    Bankstahl, Marion
    Kuntner, Claudia
    Stanek, Johann
    Wanek, Thomas
    Meier, Martin
    Ding, Xiao-Qi
    Mueller, Markus
    Langer, Oliver
    Loescher, Wolfgang
    JOURNAL OF NEUROSCIENCE, 2011, 31 (24): : 8803 - 8811
  • [25] The functional role of P-glycoprotein in the blood-brain barrier
    vanAsperen, J
    Mayer, U
    vanTellingen, O
    Beijnen, JH
    JOURNAL OF PHARMACEUTICAL SCIENCES, 1997, 86 (08) : 881 - 884
  • [26] P-glycoprotein in the developing human blood-brain barrier
    Watchko, Jon F.
    PEDIATRIC RESEARCH, 2016, 79 (05) : 806 - 806
  • [27] The strongest expression of P-glycoprotein is in the blood-brain barrier
    Beaulieu, E
    Demeule, M
    AverillBates, DA
    Beliveau, R
    BIOLOGY AND PHYSIOLOGY OF THE BLOOD-BRAIN BARRIER: TRANSPORT, CELLULAR INTERACTIONS, AND BRAIN PATHOLOGIES, 1996, 46 : 171 - 174
  • [28] Imaging P-glycoprotein at the human blood-brain barrier
    Franssen, Eric J. F.
    Luurtsema, Gert
    Lammertsma, Adriaan A.
    CLINICAL PHARMACOLOGY & THERAPEUTICS, 2006, 80 (03) : 302 - 303
  • [29] Oseltamivir (Tamiflu) efflux transport at the blood-brain barrier via P-glycoprotein
    Morimoto, Kaori
    Nakakariya, Masanori
    Shirasaka, Yoshiyuki
    Kakinuma, Chihaya
    Fujita, Takuya
    Tamai, Ikumi
    Ogihara, Takuo
    DRUG METABOLISM AND DISPOSITION, 2008, 36 (01) : 6 - 9
  • [30] Modulation of P-glycoprotein transport activity in the mouse blood-brain barrier by rifampin
    Zong, J
    Pollack, GM
    JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS, 2003, 306 (02): : 556 - 562