Focal adhesions: structure and dynamics

被引：274
|
作者：
Petit, V [1 ]
Thiery, JP [1 ]
机构：
[1] Inst Curie, CNRS, UMR 144, Div Res, F-75248 Paris 05, France
来源：
BIOLOGY OF THE CELL | 2000年 / 92卷 / 07期
关键词：
focal adhesion; integrins; extracellular matrix; Rho;
D O I：
10.1016/S0248-4900(00)01101-1
中图分类号：
Q2 [细胞生物学];
学科分类号：
071009 ; 090102 ;
摘要：
Interactions of cells with the extracellular matrix are essential for the control of tissue remodelling, cell migration, and embryogenesis. At the cell-extracellular matrix contact points, specialized structures are formed and termed focal adhesions, where transmembrane adhesion receptors provide a structural link between the actin cytoskeleton and the extracellular matrix components. Numerous structural and regulatory proteins assemble at the cytoplasmic face of focal adhesions in a Rho-dependent fashion. (C) 2000 Editions scientifiques et medicales Elsevier SAS.
引用
收藏
页码：477 / 494
页数：18
相关论文
共 50 条
  • [21] Focal adhesions in osteoneogenesis
    Biggs, M. J. P.
    Dalby, M. J.
    PROCEEDINGS OF THE INSTITUTION OF MECHANICAL ENGINEERS PART H-JOURNAL OF ENGINEERING IN MEDICINE, 2010, 224 (H12) : 1441 - 1453
  • [22] Translation at focal adhesions
    LeBrasseur, Nicole
    JOURNAL OF CELL BIOLOGY, 2008, 180 (04): : 658 - 658
  • [23] FAK Structure and Regulation by Membrane Interactions and Force in Focal Adhesions
    Martinez, Paula Tapial
    Navajas, Pilar Lopez
    Lietha, Daniel
    BIOMOLECULES, 2020, 10 (02)
  • [24] TES of the focal adhesions
    Greaves, S
    NATURE CELL BIOLOGY, 2003, 5 (04) : 279 - 279
  • [25] Mechanotransduction and focal adhesions
    Goldmann, Wolfgang H.
    CELL BIOLOGY INTERNATIONAL, 2012, 36 (07) : 649 - 652
  • [26] TES of the focal adhesions
    Sarah Greaves
    Nature Cell Biology, 2003, 5 : 279 - 279
  • [27] Dynamics and Mechanism of p130Cas Localization to Focal Adhesions
    Donato, Dominique M.
    Ryzhova, Larisa M.
    Meenderink, Leslie M.
    Kaverina, Irina
    Hanks, Steven K.
    JOURNAL OF BIOLOGICAL CHEMISTRY, 2010, 285 (27) : 20769 - 20779
  • [28] FOCAL ADHESIONS DYNAMICS IN MALIGNANT GLIAL CELLS WITH VARIABLE DRR EXPRESSION
    Ajlan, Abdulrazzag
    Husaine, S.
    Petrecca, K.
    NEURO-ONCOLOGY, 2010, 12 : 7 - 7
  • [29] Bidirectional control of the inner dynamics of focal adhesions promotes cell migration
    Goetz, Jacky G.
    CELL ADHESION & MIGRATION, 2009, 3 (02) : 185 - 190
  • [30] Dynamics of focal adhesions in osteoblastic cells are controlled by characteristics of biomaterial surfaces
    Diener, A
    Nebe, B
    Lüthen, F
    Becker, P
    Neumann, HG
    Rychly, J
    EUROPEAN JOURNAL OF CELL BIOLOGY, 2004, 83 : 34 - 34
12345